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Report of cold agglutinins in a patient with acute ischemic stroke
Jin, Haiqiang; Sun, Wei; Sun, Yongan; Huang, Yining; Sun, Yunchuang
关键词Cold agglutinin disease Acute ischemic stroke
刊名BMC NEUROLOGY
2015-10-30
DOI10.1186/s12883-015-0482-2
15
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Clinical Neurology
研究领域[WOS]Neurosciences & Neurology
关键词[WOS]DISEASE
英文摘要

Background: Studies on the role of cold agglutinins in the pathogenesis of acute ischemic stroke are scarce. We present a case of an elderly man with acute cerebral infarction probably due to cold agglutinin disease.

Case presentation: On a cold morning, a 71-year-old male of Han nationality with a complaint of sudden onset left-sided weakness and difficulty in speaking was brought to the emergency department. Diffusion weighted magnetic resonance imaging of the brain showed a high-intensity area in the right basal ganglia and corona radiata. Laboratory test showed the presence of high titers of cold agglutinins. There was no history of common risk factors of atherosclerosis, such as hypertension, diabetes mellitus, coronary artery disease or smoking. After being exposed to warm temperature, and with corticosteroid therapy and blood transfusion, the patient′s symptoms relieved rapidly.

Conclusion: We report here the first case of cerebral infarction probably due to the cold agglutinin disease. The underlying mechanism of cold agglutinins in the pathogenesis of acute ischemic stroke needs to be investigated further.

语种英语
WOS记录号WOS:000365296100001
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63807
专题北京大学第一临床医学院_神经内科
作者单位Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Jin, Haiqiang,Sun, Wei,Sun, Yongan,et al. Report of cold agglutinins in a patient with acute ischemic stroke[J]. BMC NEUROLOGY,2015,15.
APA Jin, Haiqiang,Sun, Wei,Sun, Yongan,Huang, Yining,&Sun, Yunchuang.(2015).Report of cold agglutinins in a patient with acute ischemic stroke.BMC NEUROLOGY,15.
MLA Jin, Haiqiang,et al."Report of cold agglutinins in a patient with acute ischemic stroke".BMC NEUROLOGY 15(2015).
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