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学科主题: 临床医学
题名:
Report of cold agglutinins in a patient with acute ischemic stroke
作者: Jin, Haiqiang; Sun, Wei; Sun, Yongan; Huang, Yining; Sun, Yunchuang
关键词: Cold agglutinin disease ; Acute ischemic stroke
刊名: BMC NEUROLOGY
发表日期: 2015-10-30
DOI: 10.1186/s12883-015-0482-2
卷: 15
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Clinical Neurology
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: DISEASE
英文摘要:

Background: Studies on the role of cold agglutinins in the pathogenesis of acute ischemic stroke are scarce. We present a case of an elderly man with acute cerebral infarction probably due to cold agglutinin disease.

Case presentation: On a cold morning, a 71-year-old male of Han nationality with a complaint of sudden onset left-sided weakness and difficulty in speaking was brought to the emergency department. Diffusion weighted magnetic resonance imaging of the brain showed a high-intensity area in the right basal ganglia and corona radiata. Laboratory test showed the presence of high titers of cold agglutinins. There was no history of common risk factors of atherosclerosis, such as hypertension, diabetes mellitus, coronary artery disease or smoking. After being exposed to warm temperature, and with corticosteroid therapy and blood transfusion, the patient′s symptoms relieved rapidly.

Conclusion: We report here the first case of cerebral infarction probably due to the cold agglutinin disease. The underlying mechanism of cold agglutinins in the pathogenesis of acute ischemic stroke needs to be investigated further.

语种: 英语
WOS记录号: WOS:000365296100001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63807
Appears in Collections:北京大学第一临床医学院_神经内科_期刊论文

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作者单位: Peking Univ, Hosp 1, Dept Neurol, Beijing 100034, Peoples R China

Recommended Citation:
Jin, Haiqiang,Sun, Wei,Sun, Yongan,et al. Report of cold agglutinins in a patient with acute ischemic stroke[J]. BMC NEUROLOGY,2015,15.
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