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学科主题: 药学
题名:
Dimeric Abietane Diterpenoids and Sesquiterpenoid Lactones from Teucrium viscidum
作者: Gao, Chun1; Han, Li2; Zheng, Dan2; Jin, Hongwei1; Gai, Chunyan1; Wang, Jianbin1; Zhang, Hao1; Zhang, Liangren1; Fu, Hongzheng1
刊名: JOURNAL OF NATURAL PRODUCTS
发表日期: 2015-04-01
DOI: 10.1021/np500746n
卷: 78, 期:4, 页:630-638
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
研究领域[WOS]: Plant Sciences ; Pharmacology & Pharmacy
关键词[WOS]: SALVIA-PRIONITIS ; VAR MIQUELIANUM ; VAR. FORMOSANA ; METABOLITES ; BARK
英文摘要:

A hew abietane diterpenoid, teuvisone (2), a pair of new dimeric abietane diterpenoid stereoisomers, biteuvisones A (3) and B (4), and three new sesquiterpenoid lactones, teuvislactones A-C (6, 7, and 10), were isolated from the whole plants of Teucrium viscidum, along with four known terpenoids (1, 5, 8, and 9). The structures of the new compounds were elucidated by spectroscopic analysis, and the absolute configurations of 5-10 were determined by electronic circular dichroism analysis. The isolated compounds were evaluated for their cytotoxic effects against five human cancer cell lines and for their a-glucosidase inhibitory effects.

语种: 英语
所属项目编号: 81172943 ; 2012ZX09103201-022
项目资助者: National Natural Science Foundation of China ; National Key Scientific and Technological Special Projects
WOS记录号: WOS:000353665100005
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/63820
Appears in Collections:北京大学药学院_期刊论文

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作者单位: 1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Northeastern Univ, Coll Life & Hlth Sci, Inst Microbial Pharmaceut, Shenyang 110819, Peoples R China

Recommended Citation:
Gao, Chun,Han, Li,Zheng, Dan,et al. Dimeric Abietane Diterpenoids and Sesquiterpenoid Lactones from Teucrium viscidum[J]. JOURNAL OF NATURAL PRODUCTS,2015,78(4):630-638.
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