学科主题基础医学
The Research Advances in Small Molecules Related With Delaying Aging
Gao Ling-Yun; Li Guo-Dong; Tong Tan-Jun
关键词aging SIRT1 advanced glycosylation end products (AGEs) TOR calorie restriction (CR) drug cancer
刊名PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
2010-09-01
DOI10.3724/SP.J.1206.2010.00152
37期:9页:932-938
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]EXTENDS LIFE-SPAN ; ADULT CAENORHABDITIS-ELEGANS ; HER-2/NEU TRANSGENIC MICE ; HUMAN-DIPLOID FIBROBLASTS ; GREEN TEA COMPOUND ; ALPHA-LIPOIC ACID ; CELLULAR SENESCENCE ; SACCHAROMYCES-CEREVISIAE ; DROSOPHILA-MELANOGASTER ; CALORIC RESTRICTION
英文摘要

Screening small molecules having anti-aging effect and researching the mechanism are of great practical significance for discovering new effective targets for treatment of age-related diseases and tumors, developing new drugs and promoting human health. What is more important is that these small molecules can be used as breakthrough points for the specific molecular mechanisms of aging, cancer and other biological phenomena via in-depth study. And this has an important role in promoting the development of molecular biology and other related life sciences. This article summarizes some representative anti-aging small molecules of the past decade or two and focuses on their molecular mechanisms.

语种中文
WOS记录号WOS:000282202900002
项目编号2007CB507400 ; 30973146
资助机构National Basic Research Program of China ; National Natural Science Foundation of China
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63831
专题北京大学基础医学院_北京大学衰老研究中心
北京大学基础医学院
作者单位Peking Univ, Res Ctr Aging, Dept Biochem & Mol Biol, Hlth Sci Ctr, Beijing 100191, Peoples R China
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Gao Ling-Yun,Li Guo-Dong,Tong Tan-Jun. The Research Advances in Small Molecules Related With Delaying Aging[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2010,37(9):932-938.
APA Gao Ling-Yun,Li Guo-Dong,&Tong Tan-Jun.(2010).The Research Advances in Small Molecules Related With Delaying Aging.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,37(9),932-938.
MLA Gao Ling-Yun,et al."The Research Advances in Small Molecules Related With Delaying Aging".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 37.9(2010):932-938.
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