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Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)
Feng, Q; Chen, X; Ma, O; Liu, YY; Ding, MX; Collins, RA; Ko, LS; Xing, J; Lau, LT; Yu, ACH; Chen, JG
关键词foot-and-mouth disease VP1 protein serotype Hong Kong
刊名BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2003-03-21
DOI10.1016/S0006-291X(03)00250-X
302期:4页:715-721
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]ACID
英文摘要

The nucleotide sequence of the VP1 coding region of foot-and-mouth disease virus (FMDV) strain HKN/2002, isolated from a disease outbreak occurring in Hong Kong in February 2002, was determined and compared with the sequences of other FMDVs. The VP1 coding region was 639 nucleotides in length and encoded a protein of 213 amino acid residues. Comparison of the VP1 nucleotide sequence with those of other isolates indicated that HKN/2002 belonged to serotype O. A VPI-based sequence similarity tree of several South-east Asian FMDV-0 isolates showed that HKN/2002 was most closely related to FMDV isolates found in Hong Kong from 1991 to 1999 and Taiwan in 1997. Comparison of the amino acid sequence of the major immunogenic region of HKN/2002 with that of the serotype 0 vaccine strain, O1/Manisa/Turkey/69, reveals significant similarity, indicating that current serotype 0 vaccines may offer some degree of protection against HKN/2002. (C) 2003 Elsevier Science (USA). All rights reserved.

语种英语
WOS记录号WOS:000181881300013
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被引频次:13[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63882
专题北京大学基础医学院_神经生物学系
作者单位1.Peking Univ, Neurosci Res Inst, Beijing 100083, Peoples R China
2.Peking Univ, Dept Neurobiol, Beijing 100083, Peoples R China
3.Hong Kong DNA Chips Ltd, Kowloon, Hong Kong, Peoples R China
4.Peking Univ, Coll Life Sci, Dept Cell Biol & Genet, Beijing 100871, Peoples R China
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GB/T 7714
Feng, Q,Chen, X,Ma, O,et al. Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2003,302(4):715-721.
APA Feng, Q.,Chen, X.,Ma, O.,Liu, YY.,Ding, MX.,...&Chen, JG.(2003).Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002).BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,302(4),715-721.
MLA Feng, Q,et al."Serotype and VP1 gene sequence of a foot-and-mouth disease virus from Hong Kong (2002)".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 302.4(2003):715-721.
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