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学科主题临床医学
Comparison of Diffusion-Weighted with T2-weighted Imaging for Detection of Small Hepatocellular Carcinoma in Cirrhosis: Preliminary Quantitative Study at 3-T
Wang, Hua1,2; Wang, Xiao-Ying1; Jiang, Xue-Xiang1; Ye, Zhao-Xiang2
关键词Diffusion-weighted imaging magnetic resonance hepatocellular carcinoma cirrhosis
刊名ACADEMIC RADIOLOGY
2010-02-01
DOI10.1016/j.acra.2009.09.012
17期:2页:239-243
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]ECHO-PLANAR MR ; LIVER LESION DETECTION ; FOCAL HEPATIC-LESIONS ; BREATH-HOLD ; INITIAL-EXPERIENCE ; 3.0 T ; SEQUENCES ; ECHOPLANAR ; DIAGNOSIS ; FIBROSIS
英文摘要

Rationale and Objectives: To compare diffusion-weighted (DW) with standard T2-weighted imaging for quantitative evaluation of small hepatocellular carcinoma (HCC) in cirrhosis.

Materials and Methods: Fourteen patients (all men; mean age, 58.6 years; age range, 45-69 years) with 22 small HCCs (<3 cm and >1 cm in diameter) in cirrhosis were included in the study. DW imaging with breath-hold single-shot echo planar imaging (b = 0, 800 seconds/mm(2)) and T2-weighted imaging with respiratory triggering fat-suppressed fast spin-echo sequence were performed on a 3-T magnetic resonance unit using an eight-channel torso phased-array coil. The signal intensity (SI) of HCC and liver were measured at workstation. Contrast-to-noise ratio (CNR), contrast ratio (CR, Sl(lesion)/Sl(liver)), and apparent diffusion coefficient (ADC) values were calculated. CNRs and CRs obtained with DW and T2-weighted images, and ADCs of HCC and liver were compared using nonparametric tests.

Results: Two lesions were excluded because of artifacts on DW images. Thus 20 lesions were analyzed. The CNRs obtained with T2-weighted images (27.12 +/- 21.12) were significantly higher (P = .02) than those with DW images (17.52 +/- 13.50). There were no significant difference between the CRs obtained with T2-weighted images (1.83 +/- 0.56) and DW images (2.01 +/- 0.67). There were no significant difference between the mean ADCs of HCC (1.22 x 10(-3) mm(2)/second +/- 0.24) and the cirrhotic liver (1.17 x 10(-3) mm(2)/second +/- 0.17), either.

Conclusion: DW imaging with high b value was not superior to standard T2-weighted imaging in terms of lesion conspicuity of small HCC in cirrhosis.

语种英语
WOS记录号WOS:000273834100016
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63935
专题北京大学第一临床医学院_放射治疗科
北京大学第一临床医学院_医学影像科
作者单位1.Peking Univ, Hosp 1, Dept Radiol, Beijing 100871, Peoples R China
2.Tianjin Med Univ, Canc Inst & Hosp, Dept Radiol, Tianjin 300060, Peoples R China
推荐引用方式
GB/T 7714
Wang, Hua,Wang, Xiao-Ying,Jiang, Xue-Xiang,et al. Comparison of Diffusion-Weighted with T2-weighted Imaging for Detection of Small Hepatocellular Carcinoma in Cirrhosis: Preliminary Quantitative Study at 3-T[J]. ACADEMIC RADIOLOGY,2010,17(2):239-243.
APA Wang, Hua,Wang, Xiao-Ying,Jiang, Xue-Xiang,&Ye, Zhao-Xiang.(2010).Comparison of Diffusion-Weighted with T2-weighted Imaging for Detection of Small Hepatocellular Carcinoma in Cirrhosis: Preliminary Quantitative Study at 3-T.ACADEMIC RADIOLOGY,17(2),239-243.
MLA Wang, Hua,et al."Comparison of Diffusion-Weighted with T2-weighted Imaging for Detection of Small Hepatocellular Carcinoma in Cirrhosis: Preliminary Quantitative Study at 3-T".ACADEMIC RADIOLOGY 17.2(2010):239-243.
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