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Meta-analysis on autologous stem cell transplantation in the treatment of limb ischemic
Sun, Xiuqin1; Ying, Jilin2; Wang, Yunan3; Li, Wei5; Wu, Yaojiang4; Yao, Baoting3; Liu, Ying3; Gao, Hongkai6; Zhang, Xiaomei7
关键词Stem cell limb ischemic meta-analysis
刊名INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2015
8期:6页:8740-8748
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, Research & Experimental
研究领域[WOS]Research & Experimental Medicine
关键词[WOS]PERIPHERAL ARTERIAL-DISEASE ; DOUBLE-BLIND ; MYELOMA PATIENTS ; THERAPY ; TRIAL ; ANGIOGENESIS ; NEOVASCULARIZATION ; MULTICENTER ; HINDLIMB ; PLACEBO
英文摘要

Aim: Meta-analysis on the effectiveness of the autologous stem cell transplantation in curing limb ischemic. Method: Consulting papers relate to the autologous stem cell transplantation in curing limb ischemic in PubMed, CNKI, Wan-fang Data and VIP. Based on include and exclude standards, we arrange at least 2 evaluators sifting these papers separately, doing Quality evaluation and information extraction and then cross checking. Negotiate through a third party if any disagreement comes out. Review Manager 4.2 is used in Meta-analysis. Result: Involved 7 papers, all in English version. Patients involved all diagnosed as critical limb ischemia (CLI). Results show that no adverse reaction occurred during this study. Amputation rate in patients with stem cell group treatment is lower than control group (P < 0.05). And no notable difference in improving ABI (P > 0.05). Conclusions: Applying autologous stem cell transplantation in curing limb ischemic does not have obviously effectiveness in the improvement of ABI of the limb ischemic patients. But it can dramatically reduce the rate of amputation. So autologous stem cell transplantation is a good and safe choice for patients have no choice but amputation.

语种英语
WOS记录号WOS:000359295600043
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/63996
专题北京大学国际医院
作者单位1.Capital Med Univ, Dept Endocrinol & Metab, Anzhen Hosp Beijing, Beijing, Peoples R China
2.Puren Hosp Beijing, Dept Orthoped, Beijing, Peoples R China
3.First Hosp Dandong, Dept Endocrinol, Liaoning, Peoples R China
4.First Hosp Dandong, Dept Gen Surg, Liaoning, Peoples R China
5.Second Mil Med Univ, Changhai Hosp, Dept Gen Surg, Shanghai, Peoples R China
6.Gen Hosp Armed Police, Dept Gen Surg, Beijing, Peoples R China
7.Peking Univ, Int Hosp, Dept Endocrinol & Metab, Beijing 100871, Peoples R China
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GB/T 7714
Sun, Xiuqin,Ying, Jilin,Wang, Yunan,et al. Meta-analysis on autologous stem cell transplantation in the treatment of limb ischemic[J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,2015,8(6):8740-8748.
APA Sun, Xiuqin.,Ying, Jilin.,Wang, Yunan.,Li, Wei.,Wu, Yaojiang.,...&Zhang, Xiaomei.(2015).Meta-analysis on autologous stem cell transplantation in the treatment of limb ischemic.INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE,8(6),8740-8748.
MLA Sun, Xiuqin,et al."Meta-analysis on autologous stem cell transplantation in the treatment of limb ischemic".INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 8.6(2015):8740-8748.
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