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Assessment of therapeutic biomarkers in the treatment of children with postural tachycardia syndrome and vasovagal syncope
Lin, Jing; Jin, Hongfang; Du, Junbao
关键词Postural tachycardia syndrome vasovagal syncope therapeutic biomarkers
刊名CARDIOLOGY IN THE YOUNG
2014-10-01
DOI10.1017/S1047951114000316
24期:5页:792-796
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Cardiac & Cardiovascular Systems ; Pediatrics
资助者National Twelfth Five-Year Plan for Science &amp ; Technology Support ; National Twelfth Five-Year Plan for Science &amp ; Technology Support
研究领域[WOS]Cardiovascular System & Cardiology ; Pediatrics
关键词[WOS]FLOW-MEDIATED VASODILATION ; ORTHOSTATIC TACHYCARDIA ; MIDODRINE HYDROCHLORIDE ; PRO-ADRENOMEDULLIN ; HYDROGEN-SULFIDE ; PLASMA ; INTOLERANCE ; PREDICTOR ; PROPRANOLOL ; ADOLESCENTS
英文摘要

Background: Postural tachycardia syndrome and vasovagal syncope are common causes of orthostatic intolerance in children. The supplementation with water, or salt, or midodrine, or beta-blocker was applied to children with postural tachycardia syndrome or vasovagal syncope. However, the efficacy of such medication varied and was not satisfied. This review aimed to summarise the current biomarkers in the treatment of the diseases. Data sources: Studies were collected from online electronic databases, including OVID Medline, PubMed, ISI Web of Science, and associated references. The main areas assessed in the included studies were clinical improvement, the cure rate, and the individualised treatment for postural tachycardia syndrome and vasovagal syncope in children. Results: Haemodynamic change during head-up tilt test, and detection of 24-hour urinary sodium excretion, flow-mediated vasodilation, erythrocytic H2S, and plasma pro-adrenomedullin as biological markers were the new ways that were inexpensive, non-invasive, and easy to test for finding those who would be suitable for a specific drug and treatment. Conclusion: With the help of biomarkers, the therapeutic efficacy was greatly increased for children with postural tachycardia syndrome and vasovagal syncope.

语种英语
所属项目编号2012BAI03B03
资助者National Twelfth Five-Year Plan for Science &amp ; Technology Support ; National Twelfth Five-Year Plan for Science &amp ; Technology Support
WOS记录号WOS:000346331200003
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64040
Collection北京大学第一临床医学院_儿科
作者单位Peking Univ, Hosp 1, Dept Pediat, Beijing 100034, Peoples R China
Recommended Citation
GB/T 7714
Lin, Jing,Jin, Hongfang,Du, Junbao. Assessment of therapeutic biomarkers in the treatment of children with postural tachycardia syndrome and vasovagal syncope[J]. CARDIOLOGY IN THE YOUNG,2014,24(5):792-796.
APA Lin, Jing,Jin, Hongfang,&Du, Junbao.(2014).Assessment of therapeutic biomarkers in the treatment of children with postural tachycardia syndrome and vasovagal syncope.CARDIOLOGY IN THE YOUNG,24(5),792-796.
MLA Lin, Jing,et al."Assessment of therapeutic biomarkers in the treatment of children with postural tachycardia syndrome and vasovagal syncope".CARDIOLOGY IN THE YOUNG 24.5(2014):792-796.
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