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学科主题: 临床医学
题名:
Fasting Plasma Glucose at 24-28 Weeks to Screen for Gestational Diabetes Mellitus New evidence from China
作者: Zhu, Wei-wei1; Fan, Ling2; Yang, Hui-xia1; Kong, Ling-ying1; Su, Shi-ping1; Wang, Zi-lian3; Hu, Ya-Li4; Zhang, Mei-hua5; Sun, Li-Zhou6; Mi, Yang7; Du, Xiu-ping8; Zhang, Hua9; Wang, Yun-hui10; Huang, Yin-ping11; Zhong, Li-ruo12; Wu, Hai-rong13; Li, Nan14; Wang, Yun-feng15; Kapur, Anil16
刊名: DIABETES CARE
发表日期: 2013-07-01
DOI: 10.2337/dc12-2465
卷: 36, 期:7, 页:2038-2040
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism
研究领域[WOS]: Endocrinology & Metabolism
关键词[WOS]: PREGNANCY ; ASSOCIATION ; ALGORITHM ; RISK
英文摘要:

OBJECTIVE-To evaluate the usefulness of a fasting plasma glucose (FPG) at 24-28 weeks′ gestation to screen for gestational diabetes mellitus (GDM).

RESEARCH DESIGN AND METHODS-The medical records and results of a 75-g 2-h oral glucose tolerance test (OGTT) of 24,854 pregnant women without known pre-GDM attending prenatal clinics in 15 hospitals in China were examined.

RESULTS-FPG cutoff value of 5.1 mmol/L identified 3,149 (12.1%) pregnant women with GDM. FPG cutoff value of 4.4 mmol/L ruled out GDM in 15,369 (38.2%) women. With use of this cutoff point, 12.2% of patients with mild GDM will be missed. The positive predictive value is 0.322, and the negative predictive value is 0.928.

CONCLUSIONS-FPG at 24-28 weeks′ gestation could be used as a screening test to identify GDM patients in low-resource regions. Women with an FPG between >= 4.4 and <= 5.0 mmol/L would require a 75-g OGTT to diagnose GDM. This would help to avoid approximately one-half (50.3%) of the formal 75-g OGTTs in China.

语种: 英语
所属项目编号: WDF10-517
项目资助者: World Diabetes Foundation
WOS记录号: WOS:000321472700039
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64075
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Shenzhen Peoples Hosp, Dept Obstet & Gynecol, Shenzhen, Peoples R China
2.Peking Univ, Dept Obstet & Gynecol, Hosp 1, Beijing 100871, Peoples R China
3.Beijing Obstet & Gynecol Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China
4.Sun Yat Sen Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Guangzhou 510275, Guangdong, Peoples R China
5.Nanjing Drum Tower Hosp, Dept Obstet & Gynecol, Nanjing, Jiangsu, P !E nal & Child Hlth Hosp Taiyuan, Dept Obstet & Gynecol, Taiyuan, Peoples R China
7.Jiangsu Prov Hosp, Dept Obstet & Gynecol, Nanjing, Jiangsu, Peoples R China
8.Shanxi Maternal & Child Hlth Care Hosp, Dept Obstet & Gynecol, Xian, Peoples R China
9.Shanxi Maternal & Child Hlth Hosp, Dept Obstet & Gynecol, Taiyuan, Peoples R China
10.Chongqing Med Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Chongqing, Peoples R China
11.Sun Yat Sen Univ, Dept Obstet & Gynecol, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong, Peoples R China
12.Wenzhou Med Coll, Dept Obstet & Gynecol, Affiliated Hosp 1, Wenzhou, Peoples R China
13.Aviat Gen Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China
14.Tongzhou Maternal & Child Hlth Hosp Beijing, Dept Obstet & Gynecol, Beijing, Peoples R China
15.Miyunxian Hosp, Dept Obstet & Gynecol, Beijing, Peoples R China
16.World Diabet Fdn, Gentofte, Denmark

Recommended Citation:
Zhu, Wei-wei,Fan, Ling,Yang, Hui-xia,et al. Fasting Plasma Glucose at 24-28 Weeks to Screen for Gestational Diabetes Mellitus New evidence from China[J]. DIABETES CARE,2013,36(7):2038-2040.
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