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学科主题临床医学
Association between arterial stiffness and peritoneal small solute transport rate
Zhe, Xing-wei; Tian, Xin-kui; Chen, Wei; Guo, Li-juan; Gu, Yue; Chen, Hui-min; Tang, Li-jun; Wang, Tao
关键词peritoneal transport rate arterial stiffness peritoneal dialysis
刊名ARTIFICIAL ORGANS
2008-05-01
DOI10.1111/j.1525-1594.2008.00562.x
32期:5页:416-419
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Engineering, Biomedical ; Transplantation
研究领域[WOS]Engineering ; Transplantation
关键词[WOS]STAGE RENAL-DISEASE ; DIALYSIS PATIENTS ; TECHNIQUE SURVIVAL ; ATHEROSCLEROSIS ; MALNUTRITION ; HEMODIALYSIS ; INFLAMMATION ; MORTALITY ; FLUID ; MEMBRANE
英文摘要

While cardiovascular disease accounts for 40-50% of the mortality in dialysis patients, and while a high peritoneal transport in continuous ambulatory peritoneal dialysis (CAPD) is an independent predictor of outcome, it is unclear if there are any links. Aortic stiffness has become established as a cardiovascular risk factor. We thus studied pulse wave velocity (PWV) in CAPD patients to explore the possible link between peritoneal small solute transport and aortic stiffness. CAPD patients (n = 76, 27 M/49 F) in our center were included in the present study. Aortic stiffness was assessed by brachial pulse pressure (PP) and carotid-femoral PWV. Patients′ peritoneal small solute transport rate was assessed by D/P(cr) at 4 h. Extracellular water over total body water (E/T ratio) was assessed by means of bioimpedance analysis. C-reactive protein was also measured. Carotid-femoral PWV was positively associated with patients′ age (r = 0.555; P < 0.01), time on peritoneal dialysis (r = 0.332; P < 0.01), diabetic status (r = 0.319; P < 0.01), D/P(cr) (r = 0.241; P < 0.05), PP (r = 0.475; P < 0.01), and E/T (r = 0.606; P < 0.01). In a multivariate regression analysis, carotid-femoral PWV was independently determined by E/T (P < 0.01), PP (P < 0.01), age (P < 0.01), and D/P(cr) (P < 0.05). D/P(cr), in addition to E/T, age, and PP, was an independent predictor of elevated carotid-femoral PWV in CAPD patients, suggesting that there might be a link between high aortic stiffness and increased peritoneal small solute transport rate.

语种英语
WOS记录号WOS:000255699900009
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64080
专题北京大学第三临床医学院_肾内科
北京大学公共卫生学院_公共卫生学院
北京大学第一临床医学院_皮肤性病科
北京大学口腔医学院_综合治疗二科
作者单位Peking Univ, Hosp 3, Div Nephrol, Beijing 100083, Peoples R China
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GB/T 7714
Zhe, Xing-wei,Tian, Xin-kui,Chen, Wei,et al. Association between arterial stiffness and peritoneal small solute transport rate[J]. ARTIFICIAL ORGANS,2008,32(5):416-419.
APA Zhe, Xing-wei.,Tian, Xin-kui.,Chen, Wei.,Guo, Li-juan.,Gu, Yue.,...&Wang, Tao.(2008).Association between arterial stiffness and peritoneal small solute transport rate.ARTIFICIAL ORGANS,32(5),416-419.
MLA Zhe, Xing-wei,et al."Association between arterial stiffness and peritoneal small solute transport rate".ARTIFICIAL ORGANS 32.5(2008):416-419.
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