IR@PKUHSC  > 北京大学基础医学院  > 药理学系
学科主题基础医学
Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum
Lin, ZB
关键词Ganoderma lucidum polysaccharide immuno-modulation mechanism
刊名JOURNAL OF PHARMACOLOGICAL SCIENCES
2005-10-01
99期:2页:144-153
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Pharmacology & Pharmacy
研究领域[WOS]Pharmacology & Pharmacy
关键词[WOS]DENDRITIC CELLS ; REISHI POLYSACCHARIDES ; ANTITUMOR ACTIVITIES ; T-LYMPHOCYTES ; FRUITING BODY ; CHINESE HERB ; MICE ; ACTIVATION ; MACROPHAGES ; EXPRESSION
英文摘要

Ganoderma lucidum (Leyss. ex Fr.) Karst. (Lingzhi or Reishi) has been used for a long time in China to prevent and treat various human diseases. G. lucidum polysaccharides extracted from G. lucidum are one of efficacious ingredient groups of G. lucidum. A number of reports have demonstrated that G. lucidum polysaccharides modulate immune function both in vivo and in vitro. The immuno-modulating effects of G. lucidum polysaccharides were extensive, including promoting the function of antigen-presenting cells, mononuclear phygocyte system, humoral immunity, and cellular immunity. Cellular and molecular mechanisms, possible receptors involved, and triggered signaling cascades have also been studied in vitro. However, whole animal experiments are still needed to further establish the mechanism of the immunomodulating effects by G. lucidum. Evidence-based clinical trials are also needed.

语种英语
WOS记录号WOS:000232842900003
Citation statistics
Cited Times:101[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64084
Collection北京大学基础医学院_药理学系
作者单位Peking Univ, Hlth Sci Ctr, Dept Pharmacol, Sch Basic Med Sci, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Lin, ZB. Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum[J]. JOURNAL OF PHARMACOLOGICAL SCIENCES,2005,99(2):144-153.
APA Lin, ZB.(2005).Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum.JOURNAL OF PHARMACOLOGICAL SCIENCES,99(2),144-153.
MLA Lin, ZB."Cellular and molecular mechanisms of immuno-modulation by Ganoderma lucidum".JOURNAL OF PHARMACOLOGICAL SCIENCES 99.2(2005):144-153.
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