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学科主题: 临床医学
题名:
Arterial stiffness evaluation by cardio-ankle vascular index in hypertension and diabetes mellitus subjects
作者: Wang, Hongyu1; Liu, Jinbo1; Zhao, Hongwei1; Fu, Xiaobao1; Shang, Guangyun1; Zhou, Yingyan1; Yu, Xiaolan1; Zhao, Xujing1; Wang, Guang2; Shi, Hongyan1
关键词: Cardio-ankle vascular index ; hypertension ; diabetes mellitus
刊名: JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
发表日期: 2013-11-01
DOI: 10.1016/j.jash.2013.06.003
卷: 7, 期:6, 页:426-431
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: PULSE-WAVE VELOCITY ; AORTIC STIFFNESS ; BLOOD-PRESSURE ; PARAMETER ; CAVI
英文摘要:

Arterial stiffness is an independent predictor for vascular diseases. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. In the present study, we investigated the possible risk factors involving CAVI in hypertension and diabetes mellitus (DM) subjects. One thousand sixty-three subjects (M/F 533/530) from Shougang Corporation Examination Center were divided into four groups: healthy group (n = 639); hypertension group (n = 312); DM group (n = 58); and hypertension with DM group (n = 54). CAVI was measured by VS-1000 apparatus. Our results showed that CAVI was significantly higher in hypertension subjects with DM than in healthy and hypertension group, respectively (8.59 +/- 1.08 vs 7.23 +/- 1.10; 8.59 +/- 1.08 vs 7.94 +/- 1.33; both P < .05). CAVI was positively correlated with age, systolic blood pressure, diastolic blood pressure, pulse pressure, fasting plasma glucose, HbA1c, uric acid, total cholesterol, triglycerides in the entire group (r = 0.633, 0.280, 0.172, 0.269, 0.209, 0.254, 0.176, 0.129, 0.175; all P < .05, respectively). There was negatively correlation between CAVI and high-density lipoprotein cholesterol in the entire group (r = 0.167; P < .05). Multivariate analysis showed that age, body mass index, HbA1c, and high-density lipoprotein cholesterol were independent associating factors of CAVI in all subjects (beta = 0.699; P < .001, beta = -0.189; P = .001, beta = 0.144; P = .015, beta = -0.136; P = .019, respectively). Our present study suggested that CAVI was significantly higher in hypertension subjects with DM compared with healthy and hypertension groups. (C) 2013 American Society of Hypertension. All rights reserved.

语种: 英语
所属项目编号: 2011-4026-02 ; 2010-Y002 ; 2012Y04
项目资助者: The Capital Health Research and Development of Special ; Peking University Shougang Hospital
WOS记录号: WOS:000329272800004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64100
Appears in Collections:北京大学首钢医院_心血管内科_期刊论文

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作者单位: 1.Peking Univ, Shougang Hosp, Dept Vasc Med, Beijing 100144, Peoples R China
2.Capital Med Univ, Beijing Chaoyang Hosp, Dept Endocrinol, Beijing 100020, Peoples R China

Recommended Citation:
Wang, Hongyu,Liu, Jinbo,Zhao, Hongwei,et al. Arterial stiffness evaluation by cardio-ankle vascular index in hypertension and diabetes mellitus subjects[J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION,2013,7(6):426-431.
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