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学科主题: 临床医学
题名:
Epidemiology of gastroduodenal erosions in the general population: Endoscopic results of the systematic investigation of gastrointestinal diseases in China (SILC)
作者: Ma, Xiuqiang1; Zhao, Yanfang1; Wang, Rui1; Yan, Xiaoyan2; Li, Zhaoshen3; Zou, Duowu3; He, Jia1
关键词: China ; endoscopy ; epidemiology ; gastroduodenal erosions
刊名: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
发表日期: 2010-12-01
DOI: 10.3109/00365521.2010.510570
卷: 45, 期:12, 页:1416-1423
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: HELICOBACTER-PYLORI INFECTION ; GASTRIC-MUCOSAL EROSIONS ; ACTIVATED FACTOR-VII ; FOLLOW-UP ; RISK-FACTORS ; HEMORRHAGE ; PREVALENCE ; VOLUNTEERS ; ETIOLOGY ; ULCER
英文摘要:

Objective. Population-based endoscopic studies of gastroduodenal erosions are limited in the world. This study describes features of gastroduodenal erosions in a representative sample of the population in Shanghai, China. Material and methods. A total of 3600 individuals (aged 18-80 years) were randomly selected from the Shanghai region and asked to undergo endoscopy and provide a blood sample to test for H. pylori infection. Participants completed a general information questionnaire, and a Chinese version of the Reflux Disease Questionnaire; 20% were also invited to complete the 36-item Short Form Health Survey and Epworth Sleepiness Scale. Associations between gastroduodenal erosions and other factors were analyzed using a multiple logistic regression model. Results. In total, 3153 individuals (87.6%) completed the survey and provided blood samples, 1030 (32.7%) agreed for endoscopy and 1022 participants were suitable for analysis. In all, 510 participants (49.9%) had gastroduodenal erosions (502 with gastric erosions; 26 with duodenal erosions). No significant association was found between H. pylori infection and gastroduodenal erosions. Increasing age, increasing BMI and current smoking were independent predictors for the presence of gastric erosions, but not of duodenal erosions. Duodenal erosions were more prevalent among men, which were not found in gastric erosions. The majority of individuals with gastroduodenal erosions were asymptomatic. Conclusions. Gastroduodenal erosions are more common in China than in Europe, North America, and South America. No significant association was found between H. pylori infection and gastroduodenal erosions in China. The majority of individuals with gastroduodenal erosions were asymptomatic.

语种: 英语
项目资助者: AstraZeneca R&amp ; D, Molndal, Sweden ; AstraZeneca
WOS记录号: WOS:000284268700004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64103
Appears in Collections:北京大学临床研究所_期刊论文

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作者单位: 1.Second Mil Med Univ, Dept Hlth Stat, Shanghai 200433, Peoples R China
2.Peking Univ, Clin Res Inst, Beijing 100871, Peoples R China
3.Second Mil Med Univ, Changhai Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China

Recommended Citation:
Ma, Xiuqiang,Zhao, Yanfang,Wang, Rui,et al. Epidemiology of gastroduodenal erosions in the general population: Endoscopic results of the systematic investigation of gastrointestinal diseases in China (SILC)[J]. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY,2010,45(12):1416-1423.
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