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学科主题临床医学
Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease
Ma, Hong1,2; Xie, Rong-Ai3; Gao, Li-Jian1,2; Zhang, Jin-Ping1,2; Wu, Wei-Chun1,2; Wang, Hao1,2
关键词Words coronary artery disease left ventricular filling pressure 3-dimensional speckle-tracking echocardiography vascular ultrasound
刊名JOURNAL OF ULTRASOUND IN MEDICINE
2015-10-01
DOI10.7863/ultra.15.14.11010
34期:10页:1809-1818
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]ACUTE MYOCARDIAL-INFARCTION ; CARDIAC RESYNCHRONIZATION THERAPY ; END-DIASTOLIC PRESSURE ; GLOBAL AREA STRAIN ; SYSTOLIC FUNCTION ; HEART-FAILURE ; NONCOMPACTION CARDIOMYOPATHY ; HYPERTROPHIC CARDIOMYOPATHY ; MAGYAR-PATH ; DEFORMATION
英文摘要

Objectives-The purpose of this study was to investigate the diagnostic value of 3-dimensional (3D) speckle-tracking echocardiography for estimating left ventricular filling pressure in patients with coronary artery disease (CAD) and a preserved left ventricular ejection fraction.

Methods-Altogether, 84 patients with CAD and 30 age- and sex-matched healthy control participants in sinus rhythm were recruited prospectively. All participants underwent conventional and 3D speckle-tracking echocardiography. Global strain values were automatically calculated by 3D speckle-tracking analysis. The left ventricular end-diastolic pressure (LVEDP) was determined invasively by left heart catheterization. Echocardiography and cardiac catheterization were performed within 24 hours.

Results-Compared with the controls, patients with CAD showed lower global longitudinal strain, global circumferential strain, global area strain, and global radial strain. Patients with CAD who had an elevated LVEDP had much lower levels of all 4 3D-speckle-tracking echocardiographic variables. Pearson correlation analysis revealed that the LVEDP correlated positively with the early transmitral flow velocity/early diastolic myocardial velocity (E/E′) ratio, global longitudinal strain, global circumferential strain, and global area strain. It correlated negatively with global radial strain. Receiver operating characteristic curve analysis revealed that these 3D speckle-tracking echocardiographic indices could effectively predict elevated left ventricular filling pressure (LVEDP >15 mm Hg) in patients with CAD (areas under the curve: global longitudinal strain, 0.78; global radial strain, 0.77; global circumferential strain, 0.75; and global area strain, 0.74). These parameters, however, showed no advantages over the commonly used E/E′ ratio (area under the curve, 0.84).

Conclusions-Three-dimensional speckle-tracking echocardiography was a practical technique for predicting elevated left ventricular filling pressure, but it might not be superior to the commonly used E/E′ ratio in patients with CAD who have a normal left ventricular ejection fraction.

语种英语
WOS记录号WOS:000362622800013
项目编号81201108
资助机构National Nature Science Foundation of China
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64110
专题北京大学首钢医院_心血管内科
作者单位1.Chinese Acad Med Sci, Dept Echocardiog, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Dis,Fuwai Hosp, Beijing 100037, Peoples R China
2.Peking Union Med Coll, Beijing 100021, Peoples R China
3.Peking Univ, Dept Cardiol, Shougang Hosp, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Ma, Hong,Xie, Rong-Ai,Gao, Li-Jian,et al. Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2015,34(10):1809-1818.
APA Ma, Hong,Xie, Rong-Ai,Gao, Li-Jian,Zhang, Jin-Ping,Wu, Wei-Chun,&Wang, Hao.(2015).Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease.JOURNAL OF ULTRASOUND IN MEDICINE,34(10),1809-1818.
MLA Ma, Hong,et al."Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease".JOURNAL OF ULTRASOUND IN MEDICINE 34.10(2015):1809-1818.
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