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学科主题: 临床医学
题名:
Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease
作者: Ma, Hong1,2; Xie, Rong-Ai3; Gao, Li-Jian1,2; Zhang, Jin-Ping1,2; Wu, Wei-Chun1,2; Wang, Hao1,2
关键词: Words coronary artery disease ; left ventricular filling pressure ; 3-dimensional speckle-tracking echocardiography ; vascular ultrasound
刊名: JOURNAL OF ULTRASOUND IN MEDICINE
发表日期: 2015-10-01
DOI: 10.7863/ultra.15.14.11010
卷: 34, 期:10, 页:1809-1818
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Acoustics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: ACUTE MYOCARDIAL-INFARCTION ; CARDIAC RESYNCHRONIZATION THERAPY ; END-DIASTOLIC PRESSURE ; GLOBAL AREA STRAIN ; SYSTOLIC FUNCTION ; HEART-FAILURE ; NONCOMPACTION CARDIOMYOPATHY ; HYPERTROPHIC CARDIOMYOPATHY ; MAGYAR-PATH ; DEFORMATION
英文摘要:

Objectives-The purpose of this study was to investigate the diagnostic value of 3-dimensional (3D) speckle-tracking echocardiography for estimating left ventricular filling pressure in patients with coronary artery disease (CAD) and a preserved left ventricular ejection fraction.

Methods-Altogether, 84 patients with CAD and 30 age- and sex-matched healthy control participants in sinus rhythm were recruited prospectively. All participants underwent conventional and 3D speckle-tracking echocardiography. Global strain values were automatically calculated by 3D speckle-tracking analysis. The left ventricular end-diastolic pressure (LVEDP) was determined invasively by left heart catheterization. Echocardiography and cardiac catheterization were performed within 24 hours.

Results-Compared with the controls, patients with CAD showed lower global longitudinal strain, global circumferential strain, global area strain, and global radial strain. Patients with CAD who had an elevated LVEDP had much lower levels of all 4 3D-speckle-tracking echocardiographic variables. Pearson correlation analysis revealed that the LVEDP correlated positively with the early transmitral flow velocity/early diastolic myocardial velocity (E/E′) ratio, global longitudinal strain, global circumferential strain, and global area strain. It correlated negatively with global radial strain. Receiver operating characteristic curve analysis revealed that these 3D speckle-tracking echocardiographic indices could effectively predict elevated left ventricular filling pressure (LVEDP >15 mm Hg) in patients with CAD (areas under the curve: global longitudinal strain, 0.78; global radial strain, 0.77; global circumferential strain, 0.75; and global area strain, 0.74). These parameters, however, showed no advantages over the commonly used E/E′ ratio (area under the curve, 0.84).

Conclusions-Three-dimensional speckle-tracking echocardiography was a practical technique for predicting elevated left ventricular filling pressure, but it might not be superior to the commonly used E/E′ ratio in patients with CAD who have a normal left ventricular ejection fraction.

语种: 英语
所属项目编号: 81201108
项目资助者: National Nature Science Foundation of China
WOS记录号: WOS:000362622800013
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64110
Appears in Collections:北京大学首钢医院_心血管内科_期刊论文

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作者单位: 1.Chinese Acad Med Sci, Dept Echocardiog, Natl Ctr Cardiovasc Dis, State Key Lab Cardiovasc Dis,Fuwai Hosp, Beijing 100037, Peoples R China
2.Peking Union Med Coll, Beijing 100021, Peoples R China
3.Peking Univ, Dept Cardiol, Shougang Hosp, Beijing 100871, Peoples R China

Recommended Citation:
Ma, Hong,Xie, Rong-Ai,Gao, Li-Jian,et al. Prediction of Left Ventricular Filling Pressure by 3-Dimensional Speckle-Tracking Echocardiography in Patients With Coronary Artery Disease[J]. JOURNAL OF ULTRASOUND IN MEDICINE,2015,34(10):1809-1818.
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