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学科主题临床医学
Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells
Ye, Li-Ping1; Hu, Juan1; Liang, Li2; Zhang, Chun-yang1
刊名CHEMICAL COMMUNICATIONS
2014
DOI10.1039/c4cc05598e
50期:80页:11883-11886
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]ROLLING-CIRCLE AMPLIFICATION ; ISOTHERMAL AMPLIFICATION ; ULTRASENSITIVE DETECTION ; MIRNA DETECTION ; NUCLEIC-ACIDS ; DNA DETECTION ; SERS ; PROTEIN ; SCATTERING ; OLIGONUCLEOTIDES
英文摘要

We develop circular exponential amplification reaction (EXPAR)-based surface-enhanced Raman spectroscopy (SERS) for simultaneous sensitive detection of multiple microRNAs in non-small cell lung cancer cells. This method possesses distinct advantages of excellent selectivity and high sensitivity with a detection limit of as low as 0.5 fM, which has improved by as much as 6 orders of magnitude as compared with the previously reported SERS-based direct assay.

语种英语
WOS记录号WOS:000342201700023
项目编号21325523 ; 21205128 ; 433 ; 201002009 ; 2013-BYSY-CAS-007
资助机构National Natural Science Foundation of China ; Award for the Hundred Talent Program of the Chinese Academy of Sciences ; Fund for Shenzhen Engineering Laboratory of Single-molecule Detection and Instrument Development ; State Ministry of Health of China ; Peking University Third Hospital
引用统计
被引频次:32[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64112
专题北京大学第三临床医学院
北京大学第三临床医学院_肿瘤治疗中心
作者单位1.Chinese Acad Sci, Shenzhen Inst Adv Technol, Single Mol Detect & Imaging Lab, Guangzhou 518055, Guangdong, Peoples R China
2.Peking Univ, Hosp 3, Dept Tumor Chemotherapy & Radiat Sickness, Beijing 100191, Peoples R China
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GB/T 7714
Ye, Li-Ping,Hu, Juan,Liang, Li,et al. Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells[J]. CHEMICAL COMMUNICATIONS,2014,50(80):11883-11886.
APA Ye, Li-Ping,Hu, Juan,Liang, Li,&Zhang, Chun-yang.(2014).Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells.CHEMICAL COMMUNICATIONS,50(80),11883-11886.
MLA Ye, Li-Ping,et al."Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells".CHEMICAL COMMUNICATIONS 50.80(2014):11883-11886.
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