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学科主题基础医学
A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers
Lambert, Caroline2; Berlin, Ivan3; Lee, Tat-Leang4; Hee, Siew Wan5; Tan, Audrey S. L.6; Picard, David2; Han, Ji Sheng1
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2011
DOI10.1093/ecam/nen074
0页:1-8
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]NICOTINE WITHDRAWAL ; NERVE-STIMULATION ; CONTROLLED-TRIAL ; FAGERSTROM TEST ; ACUPUNCTURE ; SMOKING ; ELECTROACUPUNCTURE ; CESSATION ; QUESTIONNAIRE ; METAANALYSIS
英文摘要

The efficacy of acupuncture in smoking cessation, and its effect on the urge to smoke are unclear. We evaluated the effect of a standardized protocol of transcutaneous electric acupoint stimulations (TEAS) on alleviating the urge to smoke. Ninety-eight smokers were recruited in two double-blind studies. Participants abstained from smoking for 26 h, and were randomized to receive TEAS alternating between 2 and 100Hz at four acupoints (LI4 and PC8, PC6 and TE5) at four different intensities (10, 5, Intermittent 5 or 0 mA). The urge to smoke was assessed by the Questionnaire of Smoking Urges (QSU-Brief). In Experiment 1, the 10mA group (n = 20) was compared with the 5mA group (n = 20); the increase in smoking urges did not differ significantly. Considering the possibility that 5mA may be an active intervention, in Experiment 2, a true placebo (0mA), and a proxy of placebo [ Intermittent 5mA (i5mA)] were compared with 10 mA TEAS. In this experiment, 10mA (n = 20) TEAS showed a tendency to alleviate smoking urges compared with 0mA (n = 16), and i5 mA (n = 19) TEAS. Only when the data of smokers with Fagerstom Test for Nicotine Dependence score >= 5 were analyzed that the difference between the 10mA group and the control group (0 and i5 mA) became significant. Based on these preliminary findings, we conclude that TEAS applied on the skin may antagonize the increase in urge to smoke in abstinent-dependent smokers. It seems warranted to assess the efficacy of TEAS in smoking cessation clinical trials involving a larger population of dependent smokers.

语种英语
WOS记录号WOS:000293394900001
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64174
专题北京大学基础医学院_神经生物学系
作者单位1.Peking Univ, Neurosci Res Inst, Beijing 100083, Peoples R China
2.Moleac Pte Ltd, Singapore 138667, Singapore
3.Univ Paris 06, Serv Pharmacol, Grp Hosp Univ Pitie Salpetriere, Fac Med,Inserm,U677, Paris, France
4.Natl Univ Singapore Hosp, Dept Anaesthesia, Singapore 119074, Singapore
5.Natl Canc Ctr, Singapore 169610, Singapore
6.Natl Healthcare Grp, Singapore 149547, Singapore
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GB/T 7714
Lambert, Caroline,Berlin, Ivan,Lee, Tat-Leang,et al. A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2011(0):1-8.
APA Lambert, Caroline.,Berlin, Ivan.,Lee, Tat-Leang.,Hee, Siew Wan.,Tan, Audrey S. L..,...&Han, Ji Sheng.(2011).A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE(0),1-8.
MLA Lambert, Caroline,et al."A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE .0(2011):1-8.
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