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学科主题: 基础医学
题名:
A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers
作者: Lambert, Caroline2; Berlin, Ivan3; Lee, Tat-Leang4; Hee, Siew Wan5; Tan, Audrey S. L.6; Picard, David2; Han, Ji Sheng1
刊名: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
发表日期: 2011
DOI: 10.1093/ecam/nen074
期: 0, 页:1-8
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
关键词[WOS]: NICOTINE WITHDRAWAL ; NERVE-STIMULATION ; CONTROLLED-TRIAL ; FAGERSTROM TEST ; ACUPUNCTURE ; SMOKING ; ELECTROACUPUNCTURE ; CESSATION ; QUESTIONNAIRE ; METAANALYSIS
英文摘要:

The efficacy of acupuncture in smoking cessation, and its effect on the urge to smoke are unclear. We evaluated the effect of a standardized protocol of transcutaneous electric acupoint stimulations (TEAS) on alleviating the urge to smoke. Ninety-eight smokers were recruited in two double-blind studies. Participants abstained from smoking for 26 h, and were randomized to receive TEAS alternating between 2 and 100Hz at four acupoints (LI4 and PC8, PC6 and TE5) at four different intensities (10, 5, Intermittent 5 or 0 mA). The urge to smoke was assessed by the Questionnaire of Smoking Urges (QSU-Brief). In Experiment 1, the 10mA group (n = 20) was compared with the 5mA group (n = 20); the increase in smoking urges did not differ significantly. Considering the possibility that 5mA may be an active intervention, in Experiment 2, a true placebo (0mA), and a proxy of placebo [ Intermittent 5mA (i5mA)] were compared with 10 mA TEAS. In this experiment, 10mA (n = 20) TEAS showed a tendency to alleviate smoking urges compared with 0mA (n = 16), and i5 mA (n = 19) TEAS. Only when the data of smokers with Fagerstom Test for Nicotine Dependence score >= 5 were analyzed that the difference between the 10mA group and the control group (0 and i5 mA) became significant. Based on these preliminary findings, we conclude that TEAS applied on the skin may antagonize the increase in urge to smoke in abstinent-dependent smokers. It seems warranted to assess the efficacy of TEAS in smoking cessation clinical trials involving a larger population of dependent smokers.

语种: 英语
项目资助者: Moleac Pte Ltd.
WOS记录号: WOS:000293394900001
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64174
Appears in Collections:基础医学院_神经生物学系_期刊论文

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作者单位: 1.Peking Univ, Neurosci Res Inst, Beijing 100083, Peoples R China
2.Moleac Pte Ltd, Singapore 138667, Singapore
3.Univ Paris 06, Serv Pharmacol, Grp Hosp Univ Pitie Salpetriere, Fac Med,Inserm,U677, Paris, France
4.Natl Univ Singapore Hosp, Dept Anaesthesia, Singapore 119074, Singapore
5.Natl Canc Ctr, Singapore 169610, Singapore
6.Natl Healthcare Grp, Singapore 149547, Singapore

Recommended Citation:
Lambert, Caroline,Berlin, Ivan,Lee, Tat-Leang,et al. A Standardized Transcutaneous Electric Acupoint Stimulation for Relieving Tobacco Urges in Dependent Smokers[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2011(0):1-8.
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