北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学药学院  > 期刊论文
学科主题: 药学
题名:
Facile one-pot synthesis of ethyl 3-alkyl-4-hydroxy-2-thioxothiazoildine-4-carboxylates
作者: Ge, ZM; Li, Q; Zheng, SJ; Cheng, TM; Cui, YX; Li, RT
关键词: ethyl 3-alkyl-4-hydroxy-2-thioxothiazolidine-4-carboxylate ; primary amine ; ethyl 3-bromo-2-oxopropanoate ; one-pot synthesis ; anhydrous potassium phosphate
刊名: CHINESE JOURNAL OF CHEMISTRY
发表日期: 2006-03-01
卷: 24, 期:3, 页:381-385
收录类别: SCI ; IC
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Chemistry, Multidisciplinary
研究领域[WOS]: Chemistry
关键词[WOS]: ACETYL THIAZOLIDINETHIONE REAGENT ; ALDOL REACTIONS ; ANALOGS ; ACID
英文摘要:

Ethyl 3-alkyl-4-hydroxy-2-thioxothiazolidine-4-carboxylates were prepared in excellent yields from the reaction of corresponding primary amines with carbon disulfide and ethyl 3-bromo-2-oxopropanoate in the presence of anhydrous potassium phosphate in DMF at room temperature within 1 h. The structures of the highly functionalized products were corroborated spectroscopically JR, H-1 NMR, C-13 NMR, EI-MS) and by elemental analyses. A plausible mechanism for such type of cyclization was proposed.

语种: 英语
WOS记录号: WOS:000235990900018
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64177
Appears in Collections:北京大学药学院_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China

Recommended Citation:
Ge, ZM,Li, Q,Zheng, SJ,et al. Facile one-pot synthesis of ethyl 3-alkyl-4-hydroxy-2-thioxothiazoildine-4-carboxylates[J]. CHINESE JOURNAL OF CHEMISTRY,2006,24(3):381-385.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Ge, ZM]'s Articles
[Li, Q]'s Articles
[Zheng, SJ]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Ge, ZM]‘s Articles
[Li, Q]‘s Articles
[Zheng, SJ]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace