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学科主题: 临床医学
题名:
Dietary Saturated Fat Intake Is Negatively Associated With Weight Maintenance Among the PREMIER Participants
作者: Lin, Pao-Hwa1; Wang, Yanfang2; Grambow, Steven C.3,4; Goggins, William5; Almirall, Daniel6
刊名: OBESITY
发表日期: 2012-03-01
DOI: 10.1038/oby.2011.17
卷: 20, 期:3, 页:571-575
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Endocrinology & Metabolism ; Nutrition & Dietetics
研究领域[WOS]: Endocrinology & Metabolism ; Nutrition & Dietetics
关键词[WOS]: TYPE-2 DIABETES-MELLITUS ; INSULIN-RESISTANCE ; BODY-WEIGHT ; MEDITERRANEAN DIET ; HIGH-PROTEIN ; BLOOD-PRESSURE ; FOOD-INTAKE ; US ADULTS ; OBESITY ; WOMEN
英文摘要:

Research finding on the composition of macronutrient intakes on body weight has not been consistent. Furthermore, little research has examined the impact of subcomponents of macronutrients such as saturated fat or plant protein on body weight. The purpose of this report was to examine the impact of saturated fat, animal and plant protein, and other macronutrient intakes at the end of an intensive intervention on subsequent follow-up body weight. This is a secondary, observational data analysis using data from PREMIER, an 18-month randomized clinical trial that enrolled a total of 810 participants. Participants completed group and individual sessions designed to help them improve blood pressure (BP) control by making lifestyle changes. Dietary intakes were assessed by two 24-h diet recalls at baseline, 6, and 18 months. Body weight and physical fitness were monitored regularly. Regression models were used to examine the impact of animal or plant protein and other macronutrient intakes on subsequent body weight. After controlling for potential confounders, none of the calorie-contributing nutrient intakes at baseline was associated with subsequent weight at 6 or 18 months. However, a greater intake of saturated fat at 6 months was associated with higher weight at 18 months (P = 0.002). A greater intake of plant protein at 6 month was marginally associated with lower absolute weight at 18 month (P = 0.069). We conclude that macronutrient intakes before the intervention were not associated with subsequent body weight at 6 or 18 months. However, a lower saturated fat intake achieved after 6-month intervention predicts a lower body weight at 18 months and thus greater weight-loss maintenance.

语种: 英语
所属项目编号: UO1 HL60570 ; UO1 HL60571 ; UO1 HL60573 ; UO1 HL60574 ; UO1 HL62828
项目资助者: National Heart, Lung, and Blood Institute
WOS记录号: WOS:000300843500014
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64233
Appears in Collections:北京大学临床研究所_期刊论文

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作者单位: 1.Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
2.Peking Univ, Hlth Sci Ctr, Clin Res Inst, Beijing 100871, Peoples R China
3.Durham Vet Affairs Med Ctr, Ctr Hlth Serv Res Primary Care, Durham, NC USA
4.Duke Univ, Med Ctr, Dept Biostat & Bioinformat, Durham, NC USA
5.Chinese Univ Hong Kong, Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China
6.Univ Michigan, Inst Social Res, Survey Res Ctr, Ann Arbor, MI USA

Recommended Citation:
Lin, Pao-Hwa,Wang, Yanfang,Grambow, Steven C.,et al. Dietary Saturated Fat Intake Is Negatively Associated With Weight Maintenance Among the PREMIER Participants[J]. OBESITY,2012,20(3):571-575.
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