IR@PKUHSC  > 北京大学临床肿瘤学院  > 病理科
学科主题临床医学
Expression of 1A6 gene and its correlation with intestinal gastric carcinoma
Liu, YQ; Zhao, H; Ning, T; Ke, Y; Li, JY
刊名WORLD JOURNAL OF GASTROENTEROLOGY
2003-02-01
9期:2页:238-241
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Gastroenterology & Hepatology
研究领域[WOS]Gastroenterology & Hepatology
关键词[WOS]CANCER ; METAPLASIA ; CARCINOGENESIS ; CLASSIFICATION ; PROTEINS
英文摘要

AIM: To investigate the expression of 1A6 gene in the lesions during the development of intestinal gastric carcinoma.

METHODS: One hundred and thirty-six cases of intestinal metaplasia (IM) from surgical resections and biopsy were classified by mucous staining. Expression of 1A6 in all cases was detected using immunohistochemical S-P method.

RESULTS: The positive rates of 1A6 in normal and superficial gastritis (SG), severe atrophic gastritis (SAG), type I, II, III IM, dysplasia (Dys) and intestinal gastric carcinoma (IGC) were 12.2 %, 16.7 %, 7.1 %, 22.6 %, 47.8 %, 46.9 % and 60.8 %, respectively. A significant difference among type III IM and SG, SAG, type I and II IM was found (P<0.01), the difference between type III and Dys, IGC being not significant.

CONCLUSION: As a new tumor-related gene, expression of 1A6 may be an effective parameter to predict the malignant transformation of precancerous lesion to gastric carcinoma.

语种英语
WOS记录号WOS:000180736500009
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64284
专题北京大学临床肿瘤学院_病理科
作者单位1.Peking Univ, Sch Oncol, Dept Pathol, Beijing 100036, Peoples R China
2.Peking Univ, Genet Lab, Sch Oncol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Liu, YQ,Zhao, H,Ning, T,et al. Expression of 1A6 gene and its correlation with intestinal gastric carcinoma[J]. WORLD JOURNAL OF GASTROENTEROLOGY,2003,9(2):238-241.
APA Liu, YQ,Zhao, H,Ning, T,Ke, Y,&Li, JY.(2003).Expression of 1A6 gene and its correlation with intestinal gastric carcinoma.WORLD JOURNAL OF GASTROENTEROLOGY,9(2),238-241.
MLA Liu, YQ,et al."Expression of 1A6 gene and its correlation with intestinal gastric carcinoma".WORLD JOURNAL OF GASTROENTEROLOGY 9.2(2003):238-241.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, YQ]的文章
[Zhao, H]的文章
[Ning, T]的文章
百度学术
百度学术中相似的文章
[Liu, YQ]的文章
[Zhao, H]的文章
[Ning, T]的文章
必应学术
必应学术中相似的文章
[Liu, YQ]的文章
[Zhao, H]的文章
[Ning, T]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。