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学科主题临床医学
Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification
Li, Qingbo1; Wang, Wei1; Ling, Xiaofeng2; Wu, Jin Guang3
刊名BIOMED RESEARCH INTERNATIONAL
2013
DOI10.1155/2013/942427
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
研究领域[WOS]Biotechnology & Applied Microbiology ; Research & Experimental Medicine
关键词[WOS]ENDOSCOPIC BIOPSIES ; CELLS ; DIAGNOSIS ; SPECTRA ; TISSUES
英文摘要

Early diagnosis and early medical treatments are the keys to save the patients′ lives and improve the living quality. Fourier transform infrared (FT-IR) spectroscopy can distinguish malignant from normal tissues at the molecular level. In this paper, programs were made with pattern recognition method to classify unknown samples. Spectral data were pretreated by using smoothing and standard normal variate (SNV) methods. Leave-one-out cross validation was used to evaluate the discrimination result of support vector machine (SVM) method. A total of 54 gastric tissue samples were employed in this study, including 24 cases of normal tissue samples and 30 cases of cancerous tissue samples. The discrimination results of SVM method showed the sensitivity with 100%, specificity with 83.3%, and total discrimination accuracy with 92.2%.

语种英语
WOS记录号WOS:000323444200001
项目编号IRT0705 ; 60708026
资助机构Programs for Changjiang Scholars and Innovative Research Team (PCSIRT) in University of China ; National Natural Science Foundation
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64289
专题北京大学第三临床医学院_普通外科
作者单位1.Beihang Univ, Sch Instrumentat Sci & Optoelect Engn, Educ Minist, Precis Optomechatron Technol Key Lab, Beijing 100191, Peoples R China
2.Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100083, Peoples R China
3.Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Li, Qingbo,Wang, Wei,Ling, Xiaofeng,et al. Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification[J]. BIOMED RESEARCH INTERNATIONAL,2013.
APA Li, Qingbo,Wang, Wei,Ling, Xiaofeng,&Wu, Jin Guang.(2013).Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification.BIOMED RESEARCH INTERNATIONAL.
MLA Li, Qingbo,et al."Detection of Gastric Cancer with Fourier Transform Infrared Spectroscopy and Support Vector Machine Classification".BIOMED RESEARCH INTERNATIONAL (2013).
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