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The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones
Zhou, Wang1; Zhang, Liangren1; Jiao, Ning1,2
刊名TETRAHEDRON
2009-03-07
DOI10.1016/j.tet.2009.01.027
65期:10页:1982-1987
收录类别SCI ; IC ; CCR
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者Peking University and National Science Foundation of China ; Ph.D. Programs Foundation of Ministry of Education of China ; Peking University and National Science Foundation of China ; Ph.D. Programs Foundation of Ministry of Education of China
研究领域[WOS]Chemistry
关键词[WOS]ALKYL IODIDES ; RING LACTONES ; CYCLIZATION ; ARYL ; PALLADIUM ; LACTAMS ; INDOLONES ; CYCLOCARBONYLATION ; 4-ARYL-2-QUINOLONES ; CONDENSATIONS
英文摘要

3,4-Dihydroquinolin-2-ones are of great importance in the areas of pharmaceuticals. However, the direct intramolecular radical cyclizations of the corresponding amide compounds favor 5-exo products 2. Reports on the radical cyclization reactions producing 3,4-dihydroquinolin-2-one derivatives are limited. Herein, an efficient tandem reaction combining radical and ionic processes was developed, which provides a practical synthetic strategy for the synthesis of substituted 3,4-dihydroquinolin-2-ones from simple and readily available precursors under neutral reaction conditions. (C) 2009 Elsevier Ltd. All rights reserved.

语种英语
所属项目编号20702002 ; 20872003 ; 20070001808
资助者Peking University and National Science Foundation of China ; Ph.D. Programs Foundation of Ministry of Education of China ; Peking University and National Science Foundation of China ; Ph.D. Programs Foundation of Ministry of Education of China
WOS记录号WOS:000263945800007
Citation statistics
Cited Times:31[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64373
Collection北京大学药学院
作者单位1.Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China
2.Chinese Acad Sci, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China
Recommended Citation
GB/T 7714
Zhou, Wang,Zhang, Liangren,Jiao, Ning. The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones[J]. TETRAHEDRON,2009,65(10):1982-1987.
APA Zhou, Wang,Zhang, Liangren,&Jiao, Ning.(2009).The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones.TETRAHEDRON,65(10),1982-1987.
MLA Zhou, Wang,et al."The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones".TETRAHEDRON 65.10(2009):1982-1987.
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