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学科主题: 临床医学
题名:
Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula
作者: Tang, Xiaodong; Guo, Wei; Yang, Rongli; Wang, Yifei
关键词: Limb salvage ; Complications ; Neoplasm ; Tibia ; Fibula
刊名: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
发表日期: 2014-03-01
DOI: 10.1007/s00402-013-1909-0
卷: 134, 期:3, 页:299-304
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Orthopedics ; Surgery
研究领域[WOS]: Orthopedics ; Surgery
关键词[WOS]: ALLOGRAFT-PROSTHETIC COMPOSITE ; OSTEOARTICULAR ALLOGRAFTS ; SURGICAL-TREATMENT ; RECONSTRUCTION ; RESECTION ; REPLACEMENT ; SYSTEM
英文摘要:

Malignant tumors in proximal tibia invading fibula usually have a large tumor volume and are adjacent to the neurovascular bundles. The prognoses and functional outcomes of limb salvage for these patients are uncertain. We, therefore, asked whether patients with limb salvage surgery for malignant tumors in proximal tibia invading fibula had poorer oncological prognosis, higher complication rate, and lower postoperative functional score compared with patients without fibula invasion.

We retrospectively reviewed 129 patients with primary malignant tumors in proximal tibia. The patients were divided into two groups, i.e., with and without proximal fibula invasion. A total of 35 and 94 patients were in the group with and without fibula invasion, respectively. Data on demography, operation time, blood loss volume, complications, survival time, and postoperative function were compared between two groups.

The patients with fibula invasion had a longer mean operative time (p = 0.011), less percentage of obtaining wide surgical margin (p = 0.027), lower estimated 5-year survival rate (p = 0.05), higher tumor local recurrence rate (p = 0.042), and earlier postoperative complications (p = 0.01) than the patients without fibula invasion. The difference in postoperative functions as evaluated by the Musculoskeletal Tumor Society functional scoring system was not significant (p = 0.233).

Patients with limb salvage surgery for malignant tumors in proximal tibia invading fibula had poorer oncological prognosis, higher complication rate, and acceptable postoperative functions compared with patients without fibula invasion.

语种: 英语
WOS记录号: WOS:000331633400001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64404
Appears in Collections:北京大学第二临床医学院_骨肿瘤科_期刊论文

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作者单位: Peking Univ, Musculoskeletal Tumor Ctr, Peoples Hosp, Beijing 100044, Peoples R China

Recommended Citation:
Tang, Xiaodong,Guo, Wei,Yang, Rongli,et al. Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula[J]. ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY,2014,134(3):299-304.
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