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学科主题临床医学
Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula
Tang, Xiaodong; Guo, Wei; Yang, Rongli; Wang, Yifei
关键词Limb salvage Complications Neoplasm Tibia Fibula
刊名ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
2014-03-01
DOI10.1007/s00402-013-1909-0
134期:3页:299-304
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Orthopedics ; Surgery
研究领域[WOS]Orthopedics ; Surgery
关键词[WOS]ALLOGRAFT-PROSTHETIC COMPOSITE ; OSTEOARTICULAR ALLOGRAFTS ; SURGICAL-TREATMENT ; RECONSTRUCTION ; RESECTION ; REPLACEMENT ; SYSTEM
英文摘要

Malignant tumors in proximal tibia invading fibula usually have a large tumor volume and are adjacent to the neurovascular bundles. The prognoses and functional outcomes of limb salvage for these patients are uncertain. We, therefore, asked whether patients with limb salvage surgery for malignant tumors in proximal tibia invading fibula had poorer oncological prognosis, higher complication rate, and lower postoperative functional score compared with patients without fibula invasion.

We retrospectively reviewed 129 patients with primary malignant tumors in proximal tibia. The patients were divided into two groups, i.e., with and without proximal fibula invasion. A total of 35 and 94 patients were in the group with and without fibula invasion, respectively. Data on demography, operation time, blood loss volume, complications, survival time, and postoperative function were compared between two groups.

The patients with fibula invasion had a longer mean operative time (p = 0.011), less percentage of obtaining wide surgical margin (p = 0.027), lower estimated 5-year survival rate (p = 0.05), higher tumor local recurrence rate (p = 0.042), and earlier postoperative complications (p = 0.01) than the patients without fibula invasion. The difference in postoperative functions as evaluated by the Musculoskeletal Tumor Society functional scoring system was not significant (p = 0.233).

Patients with limb salvage surgery for malignant tumors in proximal tibia invading fibula had poorer oncological prognosis, higher complication rate, and acceptable postoperative functions compared with patients without fibula invasion.

语种英语
WOS记录号WOS:000331633400001
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64404
专题北京大学第二临床医学院_骨肿瘤科
北京大学药学院_天然药物与仿生药物国家重点实验室
作者单位Peking Univ, Musculoskeletal Tumor Ctr, Peoples Hosp, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Tang, Xiaodong,Guo, Wei,Yang, Rongli,et al. Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula[J]. ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY,2014,134(3):299-304.
APA Tang, Xiaodong,Guo, Wei,Yang, Rongli,&Wang, Yifei.(2014).Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula.ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY,134(3),299-304.
MLA Tang, Xiaodong,et al."Poor prognosis and complications are common in limb salvage surgery for malignant tumors of the proximal tibia invading the fibula".ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY 134.3(2014):299-304.
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