北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 基础医学院  > 病原生物学系  > 期刊论文
学科主题: 基础医学
题名:
Helicobacter pylori in the oral cavity and gastric mucosa: a meta-analysis
作者: Zou, Qing-Hua1; Li, Ren-Qing2
关键词: gastric mucosa ; Helicobacter pylori ; meta-analysis ; oral cavity ; oral mucosa ; saliva
刊名: JOURNAL OF ORAL PATHOLOGY & MEDICINE
发表日期: 2011-04-01
DOI: 10.1111/j.1600-0714.2011.01006.x
卷: 40, 期:4, 页:317-324
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine ; Pathology
研究领域[WOS]: Dentistry, Oral Surgery & Medicine ; Pathology
关键词[WOS]: POLYMERASE-CHAIN-REACTION ; DENTAL PLAQUE ; HIGH PREVALENCE ; PERIODONTITIS PATIENTS ; ERADICATION THERAPY ; PCR ASSAY ; INFECTION ; DNA ; COLONIZATION ; SALIVA
英文摘要:

Background:

Helicobacter pylori have been found in the oral cavity and stomach. This study is to establish whether there might be any associations between isolates of H. pylori in the oral cavity and those in the stomach by meta-analysis.

Methods:

Studies reporting raw data on the prevalence of H. pylori infection in the oral cavity in gastric H. pylori-positive and H. pylori-negative patients, in patients with gastroesophageal diseases, and in healthy individuals and studies reporting data on the eradication rate in the oral cavity or stomach, published in the English language, were identified through MEDLINE and EMBASE up to May 2010.

Results:

The prevalence of H. pylori infection in the oral cavity in gastric H. pylori-positive patients was significantly higher (45.0%) than that in gastric H. pylori-negative patients (23.9%). The pooled odds ration (OR) was 3.61 and the 95% CI was 1.91-6.82 (P < 0.0001). Different diagnostic methods produced different pooled ORs with PCR the highest (OR = 5.11, 95% CI: 2.08-12.54, P = 0.0004) and rapid urease test (RUT) the lowest (OR = 2.00, 95% CI: 0.80-5.00, P = 0.14). The 44.8% (91/203) prevalence of H. pylori infection in the oral cavity in patients with clinical and/or histological gastroesophageal diseases was significantly higher than the 13.2% (21/159) in patients with non-ulcerous dyspepsia or healthy controls (OR = 5.15, 95% CI: 2.97-8.92, P < 0.00001). The eradication efficiency in stomach is 85.8% (187/218), while in oral cavity it is only 5.7% (9/158). The OR is 55.59, P < 0.00001.

Conclusions:

There is a close relation between the infection of H. pylori in the oral cavity and stomach. H. pylori in the oral cavity are more difficult to be eradicated than in the stomach. It may be a source of reinfection.

语种: 英语
所属项目编号: 891ja-213-741-132
项目资助者: Peking University
WOS记录号: WOS:000288702800007
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64408
Appears in Collections:基础医学院_病原生物学系_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Helicobacter pylori in the oral cavity and gastric mucosa a meta-analysis.pdf(3472KB)期刊论文出版稿限制开放 联系获取全文

作者单位: 1.Peking Univ, Hlth Sci Ctr, Dept Microbiol, Beijing 100191, Peoples R China
2.Beijing Ctr Dis Control & Prevent, Beijing, Peoples R China

Recommended Citation:
Zou, Qing-Hua,Li, Ren-Qing. Helicobacter pylori in the oral cavity and gastric mucosa: a meta-analysis[J]. JOURNAL OF ORAL PATHOLOGY & MEDICINE,2011,40(4):317-324.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zou, Qing-Hua]'s Articles
[Li, Ren-Qing]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zou, Qing-Hua]‘s Articles
[Li, Ren-Qing]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace