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学科主题: 公共卫生
题名:
Natural variances in blood pressure category among Chinese adults
作者: Hu, Jihong2,3,4,5; Wu, Yangfeng1,2,3,4; Zhao, Liancheng2,3,4; Li, Ying2,3,4; Zhou, Beifan2,3,4
关键词: blood pressure ; natural changes ; hypertension ; intervention ; Chinese
刊名: HYPERTENSION RESEARCH
发表日期: 2008-05-01
卷: 31, 期:5, 页:905-911
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Peripheral Vascular Disease
研究领域[WOS]: Cardiovascular System & Cardiology
关键词[WOS]: NONHYPERTENSIVE PARTICIPANTS ; HYPERTENSION ; PROGRESSION ; PREHYPERTENSION ; PREVENTION ; POPULATION ; COHORT
英文摘要:

Little is known about the natural progression and regression of blood pressure status, even though such knowledge would help determine the best intervention strategies. Our study aimed to explore natural changes in blood pressure status in a middle-aged Chinese population. A total of 6,129 Chinese men and women, aged 35 to 59 years at baseline, from the China Multi-center Collaborative Study of Cardiovascular Epidemiology, were reexamined 6 years later to determine the probability of progression (from non-hypertension to hypertension) and regression (from hypertension to non-hypertension). The majority (80%) of non-hypertensives among the respondents in this study remained normal or pre-hypertensive; about two-thirds of stage 1 hypertensives either stayed at the same stage or regressed to non-hypertension. However, only 9% of stage 2 hypertensives regressed to non-hypertension. Multi-variable logistic regression analysis showed that the stage 1 hypertension group had a 5-fold chance of regressing to non-hypertension in comparison with the stage 2 hypertension group (odds ratio [OR] = 0.2, 95% confidence interval [CI]: 0.1-0.3), whereas the pre-hypertension group had a 4-fold likelihood of progressing to hypertension compared with normotensive subjects (OR = 4.4, 95% CI: 3.7-5.3). After excluding participants ever on drug treatment in either examinations, the OR of regression for stage 2 hypertension was over twice that for stage 1 hypertension (OR = 0.5, 95% CI: 0.3-0.7), and the possibility of progression decreased, though very slightly (OR = 4.3, 95% CI: 3.6-5.1). Weight change significantly influenced progression and regression. Alcohol drinking affected progression significantly. In conclusion, the present findings support the strategy of intensively treating stage 2 hypertension and moderately treating stage 1 hypertension. Persons with pre-hypertension should be monitored for progression and advice on lifestyle modifications should be used.

语种: 英语
WOS记录号: WOS:000258391600011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64422
Appears in Collections:北京大学公共卫生学院_期刊论文

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作者单位: 1.Ningxia Med Coll, Dept Publ Hlth, Ningxia, Peoples R China
2.Peking Univ, Sch Publ Hlth, Hlth Sci Ctr, Dept Epidemiol & Biostat, Beijing 100083, Peoples R China
3.Chinese Acad Med Sci, Cardiovasc Inst, Dept Epidemiol, Beijing 100037, Peoples R China
4.Chinese Acad Med Sci, Fuwai Hosp, Beijing 100037, Peoples R China
5.Peking Union Med Coll, Beijing 100021, Peoples R China

Recommended Citation:
Hu, Jihong,Wu, Yangfeng,Zhao, Liancheng,et al. Natural variances in blood pressure category among Chinese adults[J]. HYPERTENSION RESEARCH,2008,31(5):905-911.
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