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Three new eudesmane sesquiterpenes from Artemisia vestita
Tian, Shuai-Hua1; Chai, Xing-Yun2; Zan, Ke1; Zeng, Ke-Wu1; Tu, Peng-Fei1
关键词Artemisia vestita Eudesmane sesquiterpene Artemivestinolide X-ray diffraction
刊名CHINESE CHEMICAL LETTERS
2013-09-01
DOI10.1016/j.cclet.2013.05.020
24期:9页:797-800
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Multidisciplinary
研究领域[WOS]Chemistry
关键词[WOS]NATURAL SESQUITERPENOIDS ; DIMERIC GUAIANOLIDES ; LACTONES ; ANOMALA
英文摘要

Three eudesmane sesquiterpene lactones, namely artemivestinolides A-C (1-3), along with three known 11-epimeric lactones (4-6), were isolated from the aerial parts of Artemisia vestita. Their structures were elucidated on the basis of extensive spectroscopic analyses (IR, HR-ESIMS, 1D NMR and 2D NMR), and the absolute configurations were determined by single-crystal X-ray diffraction (with copper radiation). Furthermore, in an in vitro assay, the three new compounds exhibited a moderate inhibition of the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in BV-2 microglial cells. (C) 2013 Peng-Fei Tu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

语种英语
WOS记录号WOS:000323589600008
项目编号30973629 ; 2012ZX09301002-002-002 ; 2012ZX09304-005
资助机构National Natural Science Foundation of China ; National Key Technology R&amp ; D Program "New Drug Innovation" of China
引用统计
被引频次:7[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64477
专题北京大学药学院
北京大学药学院_天然药物学系
作者单位1.Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Hlth Sci Ctr, Beijing 100191, Peoples R China
2.Beijing Univ Chinese Med, Modern Res Ctr Tradit Chinese Med, Beijing 100029, Peoples R China
推荐引用方式
GB/T 7714
Tian, Shuai-Hua,Chai, Xing-Yun,Zan, Ke,et al. Three new eudesmane sesquiterpenes from Artemisia vestita[J]. CHINESE CHEMICAL LETTERS,2013,24(9):797-800.
APA Tian, Shuai-Hua,Chai, Xing-Yun,Zan, Ke,Zeng, Ke-Wu,&Tu, Peng-Fei.(2013).Three new eudesmane sesquiterpenes from Artemisia vestita.CHINESE CHEMICAL LETTERS,24(9),797-800.
MLA Tian, Shuai-Hua,et al."Three new eudesmane sesquiterpenes from Artemisia vestita".CHINESE CHEMICAL LETTERS 24.9(2013):797-800.
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