IR@PKUHSC  > 北京大学第三临床医学院
学科主题临床医学
Aspergillus flavus myositis in a patient after liver transplantation
Li, Dong Ming1,3,4; Xiu, Dian Rong2; Li, Ruo Yu3; Samson, R. A.4; de Hoog, G. S.4; Wang, Duan Li3
关键词aspergillosis Aspergillus flavus liver transplantation myositis
刊名CLINICAL TRANSPLANTATION
2008-07-01
DOI10.1111/j.1399-0012.2008.00801.x
22期:4页:508-511
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Surgery ; Transplantation
研究领域[WOS]Surgery ; Transplantation
关键词[WOS]IN-VITRO ACTIVITIES ; INVASIVE ASPERGILLOSIS ; ANTIFUNGAL AGENTS ; AMPHOTERICIN-B ; FUMIGATUS ; SUSCEPTIBILITY ; INFECTIONS ; RECIPIENTS ; AIDS
英文摘要

We describe the first case of Aspergillus myositis caused by Aspergillus flavus in a liver transplant patient. The patient was a 43-year-old man who underwent liver transplantation because of end-stage hepatic cirrhosis. He experienced pain in his left calf two months after the operation. Nodules with weakness, swelling, and flaring were found in the calf two wk later. Color ultrasonic examination showed uneven resonance in the left gastrocnemius. Needle aspiration and biopsy of the muscle revealed septate hyphae consistent with Aspergillus species and focal necrosis of the muscle cells with inflammatory cell infiltration. A culture subsequently yielded A. flavus, confirming histopathologic diagnosis. Sequencing of the internal transcribed spacer region confirmed the morphologic identification. The patient was first given itraconazole 0.2 g twice daily for one wk and was then switched to terbinafine 0.25 g once a day. A three-month regimen of terbinafine therapy cured the infection, though the cultured fungus showed resistance to a number of antifungal agents. Aspergillus, a genus of ubiquitous molds, may cause invasive and even fatal disease in immunosuppressed patients.

语种英语
WOS记录号WOS:000257778600016
Citation statistics
Cited Times:13[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64512
Collection北京大学第三临床医学院
作者单位1.Peking Univ, Hosp 3, Dept Surg, Beijing 100083, Peoples R China
2.Peking Univ, Res Ctr Med Mycol, Beijing 100083, Peoples R China
3.Cent Bur Schimmelcultures, Utrecht, Netherlands
4.Peking Univ, Hosp 3, Mycol Lab Dermatol, Beijing 100083, Peoples R China
Recommended Citation
GB/T 7714
Li, Dong Ming,Xiu, Dian Rong,Li, Ruo Yu,et al. Aspergillus flavus myositis in a patient after liver transplantation[J]. CLINICAL TRANSPLANTATION,2008,22(4):508-511.
APA Li, Dong Ming,Xiu, Dian Rong,Li, Ruo Yu,Samson, R. A.,de Hoog, G. S.,&Wang, Duan Li.(2008).Aspergillus flavus myositis in a patient after liver transplantation.CLINICAL TRANSPLANTATION,22(4),508-511.
MLA Li, Dong Ming,et al."Aspergillus flavus myositis in a patient after liver transplantation".CLINICAL TRANSPLANTATION 22.4(2008):508-511.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Li, Dong Ming]'s Articles
[Xiu, Dian Rong]'s Articles
[Li, Ruo Yu]'s Articles
百度学术
百度学术Similar articles in
[Li, Dong Ming]'s Articles
[Xiu, Dian Rong]'s Articles
[Li, Ruo Yu]'s Articles
必应学术
必应学术Similar articles in
[Li, Dong Ming]'s Articles
[Xiu, Dian Rong]'s Articles
[Li, Ruo Yu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.