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学科主题: 临床医学
题名:
Effects of Beta-Blocker Use on Volume Status in Hemodialysis Patients
作者: Bi, Shu-Hong1; Linke, Lori2; Wu, Jimmy2; Cheng, Li-Tao1; Wang, Tao1; Ahmad, Suhail2
关键词: Beta-blocker ; Hypertension ; Hemodialysis ; Volume status
刊名: BLOOD PURIFICATION
发表日期: 2012
DOI: 10.1159/000337375
卷: 33, 期:4, 页:311-316
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Hematology ; Urology & Nephrology
研究领域[WOS]: Hematology ; Urology & Nephrology
关键词[WOS]: LEFT-VENTRICULAR HYPERTROPHY ; BLOOD-PRESSURE ; DRY-WEIGHT ; BIOIMPEDANCE SPECTROSCOPY ; DIALYSIS PATIENTS ; PARADOXICAL RISE ; 1ST-LINE THERAPY ; HYPERTENSION ; METAANALYSIS ; ULTRAFILTRATION
英文摘要:

Background: Removal and control of excess fluid with dialysis is considered critical for protection against cardiovascular sequelae. Antihypertensive agents including beta-blockers may influence hemodynamics, which may limit fluid removal during hemodialysis (HD). Methods: Fifty chronic HD patients underwent bioimpedance measurement before and after a midweek dialysis session. Data on volume status, blood pressure, antihypertensive medications, and bioimpedance were analyzed. Results: Patients in the high-volume status group used a significantly higher percentage of beta-blockers than patients in the low-volume status group (54.2 vs. 19.2%, respectively, p = 0.01). Multivariable regression revealed that the use of beta-blockers was independently positively associated with fluid overload (p < 0.05). Intradialytic muscle cramping occurred more often in the beta-blocker group than the control group (44.4 vs. 12.5%, respectively, p = 0.02). Conclusions: Our results suggest that the use of beta-blockers was associated with fluid overload in HD patients, and patients being treated with them experienced more intradialytic muscle cramping during dialysis. Copyright (C) 2012 S. Karger AG, Basel

语种: 英语
WOS记录号: WOS:000305810700015
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64519
Appears in Collections:北京大学第三临床医学院_肾内科_期刊论文

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作者单位: 1.Peking Univ Third Hosp, Div Nephrol, Beijing 100191, Peoples R China
2.Univ Washington, Div Nephrol, Seattle, WA 98195 USA

Recommended Citation:
Bi, Shu-Hong,Linke, Lori,Wu, Jimmy,et al. Effects of Beta-Blocker Use on Volume Status in Hemodialysis Patients[J]. BLOOD PURIFICATION,2012,33(4):311-316.
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