|Etiology and prognosis of hand eczema in a dermatology clinic in China: a follow-up study|
|Li, Lin-Feng; Liu, Guangren; Wang, Jing|
|关键词||allergic contact dermatitis eczema hand outcome patch test prognosis|
|WOS标题词||Science & Technology|
|类目[WOS]||Allergy ; Dermatology|
|研究领域[WOS]||Allergy ; Dermatology|
|关键词[WOS]||UNCLASSIFIED ENDOGENOUS ECZEMA ; CONTACT-DERMATITIS ; ASSOCIATION ; PREVALENCE|
Background: Prognosis of hand eczema (HE) has not been reported in China.
Objectives: To investigate the etiology and outcome of HE in 655 consecutive patients patch tested with European standard series in Peking University Hospital in a 2-year period.
Methods: All patients were re-examined at 1 year after patch testing, and prognosis of dermatitis was evaluated by the rate of clearance of skin symptoms for at least 3 months without relapse before the evaluation.
Results: Of 599 patients examined, 82 (13.7%) were HE. Allergic, irritant, and unclassified HE accounted for 23.2%, 17.1%, and 51.3% of HE, respectively. The overall clearance rate of HE was much lower than that of eczema elsewhere (18.3% versus 29.6%, P < 0.05, chi-squared test). 35.7% of patients with allergic HE and 26.3% with irritant HE cleared their lesions, of those with unclassified HE only 11.9% (P < 0.05, chi-squared test). The lowest healing rate (5.7%) was found in unclassified HE patients with disease duration over 6 months.
Conclusions: The outcome of HE was worse than eczema elsewhere. Allergic HE had a better prognosis than unclassified HE. Longer disease duration was the main risk factor for poor prognosis of unclassified HE.
|作者单位||Peking Univ Third Hosp, Dept Dermatol, Beijing 100083, Peoples R China|
|Li, Lin-Feng,Liu, Guangren,Wang, Jing. Etiology and prognosis of hand eczema in a dermatology clinic in China: a follow-up study[J]. CONTACT DERMATITIS,2008,58(2):88-92.|
|APA||Li, Lin-Feng,Liu, Guangren,&Wang, Jing.(2008).Etiology and prognosis of hand eczema in a dermatology clinic in China: a follow-up study.CONTACT DERMATITIS,58(2),88-92.|
|MLA||Li, Lin-Feng,et al."Etiology and prognosis of hand eczema in a dermatology clinic in China: a follow-up study".CONTACT DERMATITIS 58.2(2008):88-92.|