IR@PKUHSC  > 北京大学第二临床医学院  > 神经外科
学科主题临床医学
Changes of hypothalamus-pituitary hormones in patients after total removal of craniopharyngiomas
Zhou, ZQ; Shi, XE
关键词craniopharyngioma surgery hormone diabetes insipidus hypothyroidism
刊名CHINESE MEDICAL JOURNAL
2004-03-01
117期:3页:357-360
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]SURGICAL-MANAGEMENT ; ENDOCRINE
英文摘要

Background This paper aimed to elucidate the changes of hypothalamus-pituitary hormones in patients after total removal of craniopharyngiomas.

Methods A total of 40 patients with craniopharyngiomas received surgery. The levels of triiodothyronine (T-3), thyroxine (T-4), thyrotropic hormone (TSH), antidiuretic hormone (ADH), and adrenocorticotropin (ACTH) were measureed in the 40 patients before surgery and one week after surgery respectively.

Results Twenty-eight patients (70%) had hypothyroidism before surgery, but 38 (95%) had hypothyroidism after surgery P < 0.01). Twenty-three patients (57.5%) had diabetes insipidus ( DI) before surgery and 38 (95% had 131 after surgery ( P < 0.001). The pre- and post-operative levels of ADH were (2.49 +/- 0.30) pg/ml and (2.80 +/- 0.29) pg/ml respectively ( P > 0.05), whereas those of ACTH were (23.97 +/- 2.69) pg/ml and (15.60 +/- 1.91) pg/ml respectively (P<0.05).

Conclusions Hormone deficits after total removal of craniopharyngioma appear to be the common complication of surgery. Hypothyroidism and diabetes insipidus are more frequent after surgery than before surgery. Thyroxine and glucocorticoids should be administered routinely after total removal of craniopharyngioma.

语种英语
WOS记录号WOS:000220634700008
引用统计
被引频次:14[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64604
专题北京大学第二临床医学院_神经外科
作者单位Peking Univ, Peoples Hosp, Dept Neurosurg, Beijing 100044, Peoples R China
推荐引用方式
GB/T 7714
Zhou, ZQ,Shi, XE. Changes of hypothalamus-pituitary hormones in patients after total removal of craniopharyngiomas[J]. CHINESE MEDICAL JOURNAL,2004,117(3):357-360.
APA Zhou, ZQ,&Shi, XE.(2004).Changes of hypothalamus-pituitary hormones in patients after total removal of craniopharyngiomas.CHINESE MEDICAL JOURNAL,117(3),357-360.
MLA Zhou, ZQ,et al."Changes of hypothalamus-pituitary hormones in patients after total removal of craniopharyngiomas".CHINESE MEDICAL JOURNAL 117.3(2004):357-360.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhou, ZQ]的文章
[Shi, XE]的文章
百度学术
百度学术中相似的文章
[Zhou, ZQ]的文章
[Shi, XE]的文章
必应学术
必应学术中相似的文章
[Zhou, ZQ]的文章
[Shi, XE]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。