IR@PKUHSC  > 北京大学第二临床医学院
学科主题临床医学
Treatment Patterns and Glycemic Control in Older Adults with Type 2 Diabetes Mellitus Receiving Only Oral Antidiabetes Drugs in China
Zhang, Lihua1; Ji, Linong1; Guo, Lixin2; Lu, Juming3; Tian, Haoming4; Zhu, Dalong5; Xing, Xiaoping6; Weng, Jian Ping7; Jia, Weiping8; China Type 2 Diabetes Treatment St
刊名DIABETES TECHNOLOGY & THERAPEUTICS
2015-11-01
DOI10.1089/dia.2015.0094
17期:11页:816-824
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Endocrinology & Metabolism
研究领域[WOS]Endocrinology & Metabolism
关键词[WOS]INSULIN-SECRETION ; PREVALENCE ; MANAGEMENT ; TRANSITION ; NUTRITION ; HEALTH
英文摘要

Background: Only a few studies have reported the use of oral antidiabetes drugs (OADs) for treating older adults with type 2 diabetes mellitus (T2DM) in China. This study assessed the status of OAD therapy and relevant factors associated with OAD treatment patterns and glycemic control among older patients. Patients and Methods: We conducted a noninterventional, observational, cross-sectional, multicenter study, which was initiated by the Chinese Diabetes Society, in which 9,872 outpatients with T2DM were recruited who received OADs only. Current antidiabetes treatment regimens and related clinical data were collected from patients′ self-reporting and medical records. Participants were divided into two groups: 65 years and <65 years. All data were tabulated, and statistical analyses were performed using SPSS version 16 software (SPSS Inc., Chicago, IL). Results: Insulin secretagogues (52.6%): sulfonylureas (SU) (26.6%) and glinides (26.0%) were commonly used as monotherapy in those 65 years. The most popular OAD pattern was dual combination therapy (46.8%), with SU plus glucosidase inhibitors (25.1%) being most common in older participants. Age, diabetes duration, body mass index, achieving the glycemic control targets, and hypoglycemia were influencing factors to those 65 years in diverse treatment pattern models (P<0.05). Older patients receiving OADs with triple or more combination treatment and complications were more likely to have substandard glycemic control (hemoglobin A1c level 7%). Conclusions: The pattern of OADs alone in older adults with T2DM was significantly different from those <65 years in China. A comprehensive OAD treatment pattern or insulin combination may be necessary for better glycemic control in older patients with multiple combinations of OADs or complications.

语种英语
WOS记录号WOS:000364229300011
资助机构Novartis Pharma Co. Ltd., Beijing, China
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64644
专题北京大学第二临床医学院
作者单位1.Beijing Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing 100853, Peoples R China
3.Chinese Peoples Liberat Army Gen Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China
4.Sichuan Univ, Dept Endocrinol & Metab, West China Hosp, Chengdu 610064, Peoples R China
5.Nanjing Drum Tower Hosp, Dept Endocrinol & Metab, Nanjing, Jiangsu, Peoples R China
6.Beijing Union Med Coll Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China
7.Sun Yat Sen Univ, Affiliated Hosp 3, Dept Endocrinol & Metab, Guangzhou 510275, Guangdong, Peoples R China
8.Shanghai Jiao Tong Univ, Dept Endocrinol & Metab, Affiliated Peoples Hosp 6, Shanghai 200030, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Lihua,Ji, Linong,Guo, Lixin,et al. Treatment Patterns and Glycemic Control in Older Adults with Type 2 Diabetes Mellitus Receiving Only Oral Antidiabetes Drugs in China[J]. DIABETES TECHNOLOGY &amp; THERAPEUTICS,2015,17(11):816-824.
APA Zhang, Lihua.,Ji, Linong.,Guo, Lixin.,Lu, Juming.,Tian, Haoming.,...&China Type 2 Diabetes Treatment St.(2015).Treatment Patterns and Glycemic Control in Older Adults with Type 2 Diabetes Mellitus Receiving Only Oral Antidiabetes Drugs in China.DIABETES TECHNOLOGY & THERAPEUTICS,17(11),816-824.
MLA Zhang, Lihua,et al."Treatment Patterns and Glycemic Control in Older Adults with Type 2 Diabetes Mellitus Receiving Only Oral Antidiabetes Drugs in China".DIABETES TECHNOLOGY & THERAPEUTICS 17.11(2015):816-824.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, Lihua]的文章
[Ji, Linong]的文章
[Guo, Lixin]的文章
百度学术
百度学术中相似的文章
[Zhang, Lihua]的文章
[Ji, Linong]的文章
[Guo, Lixin]的文章
必应学术
必应学术中相似的文章
[Zhang, Lihua]的文章
[Ji, Linong]的文章
[Guo, Lixin]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。