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学科主题口腔医学
Cytokine levels in crevicular fluid are less responsive to orthodontic force in adults than in juveniles
Ren, YJ; Maltha, JC; van′ t Hof, MA; Von den Hoff, JW; Kuijpers-Jagtman, AM; Zhang, D
关键词adults cytokines GCF juveniles tooth movement
刊名JOURNAL OF CLINICAL PERIODONTOLOGY
2002-08-01
29期:8页:757-762
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dentistry, Oral Surgery & Medicine
研究领域[WOS]Dentistry, Oral Surgery & Medicine
关键词[WOS]PERIODONTAL-LIGAMENT FIBROBLASTS ; NECROSIS-FACTOR-ALPHA ; PROSTAGLANDIN-E ; TOOTH MOVEMENT ; RATS ; AGE ; INTERLEUKIN-1-BETA ; PHOSPHATASE ; RESORPTION ; ALKALINE
英文摘要

Objectives: Bone remodelling during orthodontic tooth movement is related to the expression of mediators in gingival crevicular fluid (GCF). No information is available concerning the effect of age on the levels of these mediators in GCE The purpose of this study was to quantify three mediators (prostaglandin E-2, interleukin-6 and grarmlocyte-Macrophage Colony-Stimulating Factor) in GCF during orthodontic tooth movement in juveniles and adults.

Material and methods: A total of 43 juvenile patients (mean age 11 +/- 0.7 year), and 41 adult patients (mean age 24 +/- 1.6 year) took part in the study. One of the lateral incisors of each patient was tipped labially, the other served as control. GCF samples were taken before force activation (t(0)) and 24 h later (t(24)). Mediator levels were determined by radioimmunoassay (RIA).

Results: PGE(2) concentrations were significantly elevated at t(24) in juveniles and adults, while concentrations of IL-6 and GM-CSF were significantly elevated only in juveniles. Total amounts of all three mediators in GCF significantly increased at t(24) in both groups.

Conclusions: In early tooth movement, mediator levels in juveniles are more responsive than levels in adults, which agrees with the finding that the initial tooth movement in juveniles is faster than in adults and starts without delay.

语种英语
WOS记录号WOS:000178791100013
引用统计
被引频次:40[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64664
专题北京大学口腔医学院_牙周科
作者单位1.Beijing Med Univ, Dept Orthodont, Beijing, Peoples R China
2.Univ Med Ctr St Radboud, Coll Dent Sci, Dept Orthodont & Oral Biol, NL-6500 HB Nijmegen, Netherlands
3.Univ Med Ctr St Radboud, Coll Dent Sci, Dept Prevent Dent & Cariol, NL-6500 HB Nijmegen, Netherlands
推荐引用方式
GB/T 7714
Ren, YJ,Maltha, JC,van&prime,et al. Cytokine levels in crevicular fluid are less responsive to orthodontic force in adults than in juveniles[J]. JOURNAL OF CLINICAL PERIODONTOLOGY,2002,29(8):757-762.
APA Ren, YJ.,Maltha, JC.,van&prime.,t Hof, MA.,Von den Hoff, JW.,...&Zhang, D.(2002).Cytokine levels in crevicular fluid are less responsive to orthodontic force in adults than in juveniles.JOURNAL OF CLINICAL PERIODONTOLOGY,29(8),757-762.
MLA Ren, YJ,et al."Cytokine levels in crevicular fluid are less responsive to orthodontic force in adults than in juveniles".JOURNAL OF CLINICAL PERIODONTOLOGY 29.8(2002):757-762.
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