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Characterization of Flavonoids in the Ethomedicine Fordiae Cauliflorae Radix and Its Adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn
Fan, Lan-Lan1,2; Yi, Tao1; Xu, Feng3; Zhang, Ya-Zhou2; Zhang, Jian-Ye1; Li, Dian-Peng4; Xie, Yang-Jiao5; Qin, Shan-Ding2; Chen, Hu-Biao1
关键词Fordia cauliflora Millettia pulchra var. laxior HPLC-DAD-ESI-IT-TOF-MSn flavonoids identification ethnomedicine
刊名MOLECULES
2013-12-01
DOI10.3390/molecules181215134
18期:12页:15134-15152
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Chemistry, Organic
资助者Health Department of Guangxi province ; Guangxi Administration of Traditional Chinese Medicine ; Guangxi Botanical Garden of Medicinal Plant ; Health Department of Guangxi province ; Guangxi Administration of Traditional Chinese Medicine ; Guangxi Botanical Garden of Medicinal Plant
研究领域[WOS]Chemistry
关键词[WOS]PONGAMIA-PINNATA ; LONCHOCARPUS ; ERYTHROCALYX ; CHALCONES ; GLABRA ; DERRIS ; SEEDS
英文摘要

Fordiae Cauliflorae Radix (FC, the root of Fordia cauliflora Hemsl) and Millettiae Pulchrae Radix [MP, the root of Millettia pulchra (Benth.) Kurz var. laxior (Dunn) Z. Wei], which go under the same local name of "Daluosan", have long been used in Southern China for the treatment of stroke, paralysis, dementia in children, Alzheimer′s disease and other diseases. The same local name and similar functions always confuse users. To further utilize these two ethnodrugs and identify them unambiguously, an HPLC-DAD-ESI-IT-TOF-MSn method was developed to separate and characterize the flavonoids in FC and MP. A total of 41 flavonoids were detected, of which six compounds were identified by comparing their retention time and MS data with those of the reference standards, and the others were tentatively identified based on their tandem mass spectrometry data obtained in the positive ion detection mode. Nineteen of these characterized compounds are reported from these two plants for the first time.

语种英语
所属项目编号Zhong2010111 ; Z2010175 ; GZKZ1131 ; 201109
资助者Health Department of Guangxi province ; Guangxi Administration of Traditional Chinese Medicine ; Guangxi Botanical Garden of Medicinal Plant ; Health Department of Guangxi province ; Guangxi Administration of Traditional Chinese Medicine ; Guangxi Botanical Garden of Medicinal Plant
WOS记录号WOS:000330315700045
引用统计
被引频次:4[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64715
专题北京大学药学院
作者单位1.Guangxi Bot Garden Med Plant, Nanning 530023, Guangxi, Peoples R China
2.Guangxi Univ Chinese Med, Sch Pharm, Guangxi 530001, Peoples R China
3.Hong Kong Baptist Univ, Sch Chinese Med, Kowloon, Hong Kong, Peoples R China
4.Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
5.Chinese Acad Sci, Guangxi Inst Bot, Guilin 541006, Guangxi, Peoples R China
推荐引用方式
GB/T 7714
Fan, Lan-Lan,Yi, Tao,Xu, Feng,et al. Characterization of Flavonoids in the Ethomedicine Fordiae Cauliflorae Radix and Its Adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn[J]. MOLECULES,2013,18(12):15134-15152.
APA Fan, Lan-Lan.,Yi, Tao.,Xu, Feng.,Zhang, Ya-Zhou.,Zhang, Jian-Ye.,...&Chen, Hu-Biao.(2013).Characterization of Flavonoids in the Ethomedicine Fordiae Cauliflorae Radix and Its Adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn.MOLECULES,18(12),15134-15152.
MLA Fan, Lan-Lan,et al."Characterization of Flavonoids in the Ethomedicine Fordiae Cauliflorae Radix and Its Adulterant Millettiae Pulchrae Radix by HPLC-DAD-ESI-IT-TOF-MSn".MOLECULES 18.12(2013):15134-15152.
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