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学科主题: 临床医学
题名:
Performance and optimal technique for pharyngeal impedance recording: A simulated pharyngeal reflux study
作者: Aslam, Muhammad; Bajaj, Shailesh; Easterling, Caryn; Kawamura, Osamu; Rittmann, Tanya; Hofmann, Candy; Liu, Jianxiang; Shaker, Reza
刊名: AMERICAN JOURNAL OF GASTROENTEROLOGY
发表日期: 2007
DOI: 10.1111/j.1572-0241.2006.00888.x
卷: 102, 期:1, 页:33-39
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Gastroenterology & Hepatology
研究领域[WOS]: Gastroenterology & Hepatology
关键词[WOS]: PH ; LARYNGITIS ; ACID ; OMEPRAZOLE ; SYMPTOMS ; EVENTS
英文摘要:

BACKGROUND AND AIMS: Detection rate, influence of recording site, and subject posture for impedance monitoring of pharyngeal reflux of gastric contents remain unknown. We evaluated the ability of the impedance sensor for detection of various volumes of intrapharyngeal infusate at two sites and in two subject positions.

METHODS: Nineteen healthy subjects were studied using concurrent videoendoscopic, manometric, impedance, and pH recording.

RESULTS: Detection rate of simulated pharyngeal reflux events ranged between 87% and 100% for 1-4 mL. Detection rate for 0.1-1 mL volumes in the upright position was significantly higher (78-85%) when the impedance sensor was located at the proximal margin of the upper esophageal sphincter (UES) compared to 2 cm proximally (38-68%) (P < 0.001). With the sensor at 2 cm above the UES, the average detection rate for all volumes in the upright position was significantly less (P < 0.001) compared to the supine position (48% vs 84%). There was substantial variability in the magnitude of impedance changes induced by different infusates.

CONCLUSIONS: Impedance sensors can detect as small a volume as 0.1 mL and combined with a pH sensor can detect acidic and nonacidic liquid and mist reflux events. Sensor placement at the proximal margin of the UES yields the highest detection rate irrespective of subject posture compared to placement 2 cm proximally. Depending on the volume of refluxate and location of the impedance sensor, a substantial minority of simulated reflux events can be missed.

语种: 英语
WOS记录号: WOS:000243376500007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64716
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Peking Univ, Hosp 1, Beijing 100871, Peoples R China
2.Gunma Univ, Sch Med, Gunma, Japan
3.Med Coll Wisconsin, Div Gastroenterol & Hepatol, MCW Dysphagia Inst, Milwaukee, WI 53226 USA

Recommended Citation:
Aslam, Muhammad,Bajaj, Shailesh,Easterling, Caryn,et al. Performance and optimal technique for pharyngeal impedance recording: A simulated pharyngeal reflux study[J]. AMERICAN JOURNAL OF GASTROENTEROLOGY,2007,102(1):33-39.
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