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Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys
Alonso, J.2,3; Vilagut, G.2,3; Chatterji, S.; Heeringa, S.5; Schoenbaum, M.6; Uestuen, T. Bedirhan4; Rojas-Farreras, S.2; Angermeyer, M.7; Bromet, E.8; Bruffaerts, R.9; de Girolamo, G.10; Gureje, O.11; Haro, J. M.12; Karam, A. N.13,14; Kovess, V.15; Levinson, D.16; Liu, Z.17; Medina-Mora, M. E.18; Ormel, J.19; Posada-Villa, J.20; Uda, H.21; Kessler, R. C.1
关键词Co-morbidity epidemiology global burden of disease mental health visual analog scale
刊名PSYCHOLOGICAL MEDICINE
2011-04-01
DOI10.1017/S0033291710001212
41期:4页:873-886
收录类别SCI ; SSCI
文章类型Article
WOS标题词Social Sciences ; Science & Technology
类目[WOS]Psychology, Clinical ; Psychiatry ; Psychology
研究领域[WOS]Psychology ; Psychiatry
关键词[WOS]QUALITY-OF-LIFE ; VISUAL ANALOG SCALE ; STATE VALUATIONS ; DISORDERS ; DEPRESSION ; IMPACT ; COMORBIDITY ; DISABILITY ; OUTCOMES ; VERSION
英文摘要

Background. The methodology commonly used to estimate disease burden, featuring ratings of severity of individual conditions, has been criticized for ignoring co-morbidity. A methodology that addresses this problem is proposed and illustrated here with data from the World Health Organization World Mental Health Surveys. Although the analysis is based on self-reports about one′s own conditions in a community survey, the logic applies equally well to analysis of hypothetical vignettes describing co-morbid condition profiles.

Method. Face-to-face interviews in 13 countries (six developing, nine developed; n = 31 067; response rate = 69.6%) assessed 10 classes of chronic physical and nine of mental conditions. A visual analog scale (VAS) was used to assess overall perceived health. Multiple regression analysis with interactions for co-morbidity was used to estimate associations of conditions with VAS. Simulation was used to estimate condition-specific effects.

Results. The best-fitting model included condition main effects and interactions of types by numbers of conditions. Neurological conditions, insomnia and major depression were rated most severe. Adjustment for co-morbidity reduced condition-specific estimates with substantial between-condition variation (0.24-0.70 ratios of condition-specific estimates with and without adjustment for co-morbidity). The societal-level burden rankings were quite different from the individual-level rankings, with the highest societal-level rankings associated with conditions having high prevalence rather than high individual-level severity.

Conclusions. Plausible estimates of disorder-specific effects on VAS can be obtained using methods that adjust for co-morbidity. These adjustments substantially influence condition-specific ratings.

语种英语
WOS记录号WOS:000287941200020
项目编号R01MH070884 ; HHSN271200700030C ; R13-MH066849 ; R01-MH069864 ; R01 DA016558 ; FIRCA R03-TW006481 ; QLG5-1999-01042 ; SANCO 2004123 ; FIS 00/0028 ; SAF 2000-158-CE ; CIBER CB06/02/0046 ; RETICS RD06/0011 ; H13-SHOGAI-023 ; H14-TOKUBETSU-026 ; H16-KOKORO-013 ; INPRFMDIES 4280 ; CONACyT-G30544-H ; RO1-MH61905 ; U01-MH60220 ; 044708
资助机构Bristol-Myers Squibb ; Eli Lilly Company ; GlaxoSmithKline ; Johnson &amp ; Johnson Pharmaceuticals ; Ortho-McNeil Pharmaceuticals Inc. ; Pfizer Inc. ; Sanofi-Aventis ; United States National Institute of Mental Health ; Mental Health Burden Study ; John D. and Catherine T. MacArthur Foundation ; Pfizer Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization ; Eli Lilly &amp ; Company Foundation ; Ortho-McNeil Pharmaceutical, Inc. ; Shire ; Ministry of Social Protection ; European Commission ; Piedmont Region (Italy) ; Fondo de Investigacion Sanitaria ; Instituto de Salud Carlos III, Spain ; Ministerio de Ciencia y Tecnologia, Spain ; Departament de Salut, Generalitat de Catalunya, Spain ; Instituto de Salud Carlos III ; Ministry of Health ; Japan Ministry of Health, Labor and Welfare ; Lebanese Ministry of Public Health ; WHO (Lebanon) ; Fogarty International ; Act for Lebanon ; Janssen Cilag ; Eli Lilly ; Roche ; Novartis ; National Institute of Psychiatry Ramon de la Fuente ; National Council on Science and Technology ; WHO (Geneva) ; WHO (Nigeria) ; Federal Ministry of Health, Abuja, Nigeria ; US National Institute of Mental Health ; National Institute of Mental Health (NIMH) ; Robert Wood Johnson Foundation (RWJF)
引用统计
被引频次:35[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64735
专题北京大学精神卫生研究所
作者单位1.Ctr Publ Mental Hlth, Gosing Am Wagram, Austria
2.Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium
3.IRCCS Ctr S Giovanni di Dio Fatebenefratelli, Brescia, Italy
4.Univ Coll Hosp, Ibadan, Nigeria
5.CIBERSAM, St Joan de Deu SSM, Barcelona, Spain
6.IDRAAC, Beirut, Lebanon
7.Univ Paris Descartes3, EA4069, Paris, France
8.Minist Hlth, Mental Hlth Serv, Jerusalem, Israel
9.Peking Univ, Inst Mental Hlth, Beijing 100871, Peoples R China
10.Hosp del Mar, IMIM, Hlth Serv Res Unit, Barcelona, Spain
11.CIBERESP, Barcelona, Spain
12.WHO, EIP HFS, CH-1211 Geneva, Switzerland
13.Harvard Univ, Sch Med, Dept Hlth Care Policy, Boston, MA 02115 USA
14.Univ Michigan, Inst Social Res, Ann Arbor, MI USA
15.NIMH, Bethesda, MD 20892 USA
16.SUNY Stony Brook, Stony Brook, NY 11794 USA
17.Balamand Univ, Fac Med, Dept Psychiat & Clin Psychol, St George Hosp Univ Med Ctr, Beirut, Lebanon
18.Natl Inst Psychiat Ramon de la Fuente, Mexico City, DF, Mexico
19.Univ Groningen, Univ Med Ctr Groningen, Interdisciplinary Ctr Psychiat Epidemiol, Groningen, Netherlands
20.Colegio Mayor de Cundinamarca Univ, Bogota, Colombia
21.Osumi Reg Promot Bur, Hlth Social Welf & Environm Dept, Aichi, Kagoshima, Japan
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GB/T 7714
Alonso, J.,Vilagut, G.,Chatterji, S.,et al. Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys[J]. PSYCHOLOGICAL MEDICINE,2011,41(4):873-886.
APA Alonso, J..,Vilagut, G..,Chatterji, S..,Heeringa, S..,Schoenbaum, M..,...&Kessler, R. C..(2011).Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys.PSYCHOLOGICAL MEDICINE,41(4),873-886.
MLA Alonso, J.,et al."Including information about co-morbidity in estimates of disease burden: results from the World Health Organization World Mental Health Surveys".PSYCHOLOGICAL MEDICINE 41.4(2011):873-886.
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