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学科主题: 临床医学
题名:
Exercise intervention during pregnancy can be used to manage weight gain and improve pregnancy outcomes in women with gestational diabetes mellitus
作者: Wang, Chen1; Zhu, Weiwei1,2; Wei, Yumei1; Feng, Hui1; Su, Rina1; Yang, Huixia1
关键词: Pregnancy ; Gestational diabetes mellitus ; Exercise intervention ; Dietary intervention ; Gestational weight gain ; Preterm birth ; Macrosomia ; Low birth weight ; Caesarean delivery
刊名: BMC PREGNANCY AND CHILDBIRTH
发表日期: 2015-10-12
DOI: 10.1186/s12884-015-0682-1
卷: 15
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Obstetrics & Gynecology
研究领域[WOS]: Obstetrics & Gynecology
关键词[WOS]: WORLD-HEALTH-ORGANIZATION ; DIAGNOSTIC-CRITERIA ; PHYSICAL-ACTIVITY ; FETAL-GROWTH ; MATERNAL OBESITY ; CHINESE WOMEN ; RISK ; ASSOCIATION ; CLASSIFICATION ; GUIDELINES
英文摘要:

Background: The study aimed to evaluate whether exercise intervention can be applied to pregnant women with gestational diabetes mellitus (GDM) for controlling gestational weight gain (GWG) and combating GDM-related outcomes.

Methods: Retrospective six months analysis of 14,168 single pregnant women without diabetes from 15 hospitals in Beijing in 2013. Each participant′s demographic data, interventions condition and medical information were collected individually by questionnaires and relying on medical records. The level of statistical significance was set equal to 0.05.

Results: 2750 (19.4 %) pregnant women were diagnosed with GDM, 74.9 % of them received exercise intervention during pregnancy, and the starting time was 25.8 +/- 3.7 gestational weeks. Women with GDM with exercise intervention (GDM-E) had the lowest BMI increase during late and mid-pregnancy than women with GDM without exercise intervention (GDM-nE) (2.05 +/- 1.32 kg/m(2) vs. 2.40 +/- 1.30 kg/m(2), p < 0.01) and non-GDM women (2.05 +/- 1.32 kg/m(2) vs. 2.77 +/- 1.21 kg/m(2), p < 0.01). Moreover, GDM-E group experienced a significantly lower risk of preterm birth (5.58 % vs. 7.98 %, p < 0.001), low birth weight (1.03 % vs. 2.06 %, p < 0.001) and macrosomia (9.51 % vs. 11.18 %, p > 0.05) than GDM-nE group. After including dietary factors in the analysis, women with GDM without either dietary or exercise intervention (GDM-nDnE) had the highest risk of preterm birth(OR = 1.64, 95 % CI, 1.14-2.36), while women with GDM with dietary intervention only (GDM-DnE) had the highest risk of low birth weight (OR = 3.10, 95 % CI, 1.23-7.81). However, women with GDM with both dietary and exercise intervention had the lowest rate of macrosomia.

Conclusion: Exercise intervention is a suitable non-invasive therapeutic option that can be readily applied to manage weight gain and improve pregnancy outcomes in women with GDM.

语种: 英语
所属项目编号: WDF0-57
项目资助者: "China GDM centers-Establishment and Training Dissemination" from the World Diabetes Foundation
WOS记录号: WOS:000362705000003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64762
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: 1.Natl Inst Hosp Adm, Beijing, Peoples R China
2.Peking Univ, Hosp 1, Dept Obstet & Gynecol, Beijing 100034, Peoples R China

Recommended Citation:
Wang, Chen,Zhu, Weiwei,Wei, Yumei,et al. Exercise intervention during pregnancy can be used to manage weight gain and improve pregnancy outcomes in women with gestational diabetes mellitus[J]. BMC PREGNANCY AND CHILDBIRTH,2015,15.
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