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学科主题临床医学
Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome
Jonas, Jost B.1; Hayreh, Sohan Singh2,3; Tao, Yong4; Papastathopoulos, Konstantinos I.1; Rensch, Florian1
刊名PLOS ONE
2012-05-21
DOI10.1371/journal.pone.0037499
7期:5
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Multidisciplinary Sciences
研究领域[WOS]Science & Technology - Other Topics
关键词[WOS]OPEN-ANGLE GLAUCOMA ; DISC MORPHOLOGY ; BEIJING EYE ; PARAPAPILLARY ATROPHY ; COHERENCE TOMOGRAPHY ; ADULT CHINESE ; FIBER LAYER ; PATHOGENESIS ; RATIO ; CUP
英文摘要

Purpose: To evaluate changes in cup/disc (C/D) diameter ratios and parapapillary atrophy in patients with non-arteritic anterior ischemic optic neuropathy (NA-AION), using morphometric methods.

Methods: The clinical non-interventional study included 157 patients with unilateral or bilateral NA-AION. Optic disc photographs taken from both eyes at the end of follow-up were morphometrically examined.

Results: Follow-up was 86.3 +/- 70.3 months. Horizontal and vertical disc diameters (P = 0.30; P = 0.61, respectively), horizontal and vertical C/D ratios (P = 0.47; P = 0.19, resp.), and size of alpha zone and beta zone of parapapillary atrophy (P = 0.27; P = 0.32, resp.) did not differ significantly between affected eyes and contralateral normal eyes in patients with unilateral NA-AION. Similarly, horizontal and vertical disc diameters, horizontal and vertical C/D ratios, and size of alpha zone and beta zone did not vary significantly (all P>0.05) between the unaffected eyes of patients with unilateral NA-AION and the eyes of patients with bilateral NA-AION. Optic disc diameters, C/D ratios, size of alpha zone or beta zone of parapapillary atrophy were not significantly associated with final visual outcome in the eyes affected with NA-AION (all P>0.20) nor with the difference in final visual acuity between affected eyes and unaffected eyes in patients with unilateral NA-AION (all P>0.25).

Conclusions: NA-AION did not affect C/D ratios nor alpha zone and beta zone of parapapillary atrophy. Optic disc size was not related to the final visual acuity outcome in NA-AION.

语种英语
WOS记录号WOS:000305343100036
项目编号EY-1576
资助机构U.S. National Institutes of Health ; Research to Prevent Blindness, Incorporated, New York, United States of America
引用统计
被引频次:10[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64767
专题北京大学第二临床医学院_眼科
作者单位1.Univ Iowa, Coll Med, Dept Ophthalmol, Iowa City, IA 52242 USA
2.Univ Iowa, Coll Med, Dept Visual Sci, Iowa City, IA USA
3.Univ Heidelberg, Dept Ophthalmol, Med Fac Mannheim, D-6800 Mannheim, Germany
4.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Jonas, Jost B.,Hayreh, Sohan Singh,Tao, Yong,et al. Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome[J]. PLOS ONE,2012,7(5).
APA Jonas, Jost B.,Hayreh, Sohan Singh,Tao, Yong,Papastathopoulos, Konstantinos I.,&Rensch, Florian.(2012).Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome.PLOS ONE,7(5).
MLA Jonas, Jost B.,et al."Optic Nerve Head Change in Non-Arteritic Anterior Ischemic Optic Neuropathy and Its Influence on Visual Outcome".PLOS ONE 7.5(2012).
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