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学科主题: 临床医学
题名:
Video-Assisted Thoracoscopic Left Cardiac Sympathetic Denervation: A Reliable Minimally Invasive Approach for Congenital Long-QT Syndrome
作者: Li, Jianfeng; Liu, Yanguo; Yang, Fan; Jiang, Guanchao; Li, Cuilan; Hu, Dayi; Wang, Jun1
刊名: ANNALS OF THORACIC SURGERY
发表日期: 2008-12-01
DOI: 10.1016/j.athoracsur.2008.07.100
卷: 86, 期:6, 页:1955-1959
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Cardiac & Cardiovascular Systems ; Respiratory System ; Surgery
研究领域[WOS]: Cardiovascular System & Cardiology ; Respiratory System ; Surgery
关键词[WOS]: INTERVAL ; THERAPY
英文摘要:

Background. The purpose of this study was to assess the feasibility and long-term effect of video-assisted thoracoscopic left cardiac sympathetic denervation for congenital long-QT syndrome.

Methods. From December 2002 to May 2007, 11 patients who could not tolerate or who were refractory to beta-blocker therapy received video-assisted thoracoscopic left cardiac sympathetic denervation. Under general anesthesia, the pleural cavity was entered through three 1.5-cm incisions in the left subaxillary area. The left thoracic sympathetic chain was identified, and the lower one third of the left stellate ganglion, together with T-2 to T-5 sympathetic chain, was resected.

Results. The mean operative time was 40.9 +/- 7.7 minutes. Blood loss was minimal. The mean postoperative stay was 6 +/- 1.4 days. There were no major perioperative complications apart from mild ptosis of the left upper eyelid in 1 patient who subsequently recovered shortly after the procedure. The mean follow-up time was 37.0 +/- 26.3 months. Seven of the patients are totally free of cardiac events and report good quality of life. One patient experienced decreased syncopal events from 5 or 6 times per year to 2 or 3 times per year. One patient still experiences syncopal events 3 to 4 times a year, but with shortened duration to several seconds. One patient reports syncope 10 times per year. Only 1 patient died, early in the second year after surgery. In conclusion, the overall efficacy rate (that is, reduction in syncopal episodes) is 81.8% (9 of 11) and the mortality rate, 9.1% (1 of 11).

Conclusions. Video-assisted thoracoscopic left cardiac sympathetic denervation is a simple and minimally invasive technique that results in good long-term benefits in patients with congenital long-QT syndromes.

语种: 英语
WOS记录号: WOS:000260994200035
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64855
Appears in Collections:北京大学第二临床医学院_胸外科_期刊论文

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作者单位: 1.Peking Univ, Peoples Hosp, Dept Thorac Surg, Beijing 100044, Peoples R China
2.Peking Univ, Peoples Hosp, Dept Cardiol, Beijing 100044, Peoples R China

Recommended Citation:
Li, Jianfeng,Liu, Yanguo,Yang, Fan,et al. Video-Assisted Thoracoscopic Left Cardiac Sympathetic Denervation: A Reliable Minimally Invasive Approach for Congenital Long-QT Syndrome[J]. ANNALS OF THORACIC SURGERY,2008,86(6):1955-1959.
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