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学科主题: 基础医学
题名:
Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode
作者: Li, Hong-Yu1,2,3,4; Zhang, Rong1,2,3,4; Cui, Cai-Lian1,2,3,4; Han, Ji-Sheng1,2,3,4; Wu, Liu-Zhen1,2,3,4
刊名: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
发表日期: 2011
DOI: 10.1155/2011/424092
期: 3, 页:1-5
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Integrative & Complementary Medicine
研究领域[WOS]: Integrative & Complementary Medicine
关键词[WOS]: DELTA-OPIOID RECEPTOR ; PERIPHERAL-BLOOD ; INTERFERON-GAMMA ; ACUPUNCTURE ; RATS ; STIMULATION ; ENHANCEMENT ; INVOLVEMENT ; SUPPRESSION ; INHIBITION
英文摘要:

In a previous paper we reported that electroacupuncture (EA) could suppress opioid withdrawal syndrome and increase the appetite, sleep, and body weight in heroin addicts or morphine dependent animals. Considering that opioids were known to inhibit immune function, the present study was designed to observe whether EA could modulate the immune status of morphine dependent and withdrawal mice. We found that chronic morphine-induced decrease of splenic T lymphocyte proliferation and IL-2 production can be significantly raised by 2 Hz EA, and the fluctuation of CD4(+)/CD8(+) ratio was also run to the baseline level by the EA. These findings indicated that chronic morphine exposure-induced immune dysfunction in mice could be normalized by 2 Hz EA.

语种: 英语
所属项目编号: 2007CB512500 ; 30801491
项目资助者: National Basic Research Program ; National Natural Science Foundation of China
WOS记录号: WOS:000293456800001
Citation statistics:
内容类型: 期刊论文
版本: 出版稿
URI标识: http://ir.bjmu.edu.cn/handle/400002259/64860
Appears in Collections:基础医学院_神经生物学系_期刊论文

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作者单位: 1.Peking Univ, Neurosci Res Inst, Beijing 100191, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Neurobiol, Beijing 100191, Peoples R China
3.Minist Educ, Key Lab Neurosci, Beijing 100191, Peoples R China
4.Minist Publ Hlth, Key Lab Neurosci, Beijing 100191, Peoples R China

Recommended Citation:
Li, Hong-Yu,Zhang, Rong,Cui, Cai-Lian,et al. Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2011(3):1-5.
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