IR@PKUHSC  > 北京大学基础医学院  > 神经生物学系
学科主题基础医学
Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode
Li, Hong-Yu1,2,3,4; Zhang, Rong1,2,3,4; Cui, Cai-Lian1,2,3,4; Han, Ji-Sheng1,2,3,4; Wu, Liu-Zhen1,2,3,4
刊名EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
2011
DOI10.1155/2011/424092
3页:1-5
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Integrative & Complementary Medicine
研究领域[WOS]Integrative & Complementary Medicine
关键词[WOS]DELTA-OPIOID RECEPTOR ; PERIPHERAL-BLOOD ; INTERFERON-GAMMA ; ACUPUNCTURE ; RATS ; STIMULATION ; ENHANCEMENT ; INVOLVEMENT ; SUPPRESSION ; INHIBITION
英文摘要

In a previous paper we reported that electroacupuncture (EA) could suppress opioid withdrawal syndrome and increase the appetite, sleep, and body weight in heroin addicts or morphine dependent animals. Considering that opioids were known to inhibit immune function, the present study was designed to observe whether EA could modulate the immune status of morphine dependent and withdrawal mice. We found that chronic morphine-induced decrease of splenic T lymphocyte proliferation and IL-2 production can be significantly raised by 2 Hz EA, and the fluctuation of CD4(+)/CD8(+) ratio was also run to the baseline level by the EA. These findings indicated that chronic morphine exposure-induced immune dysfunction in mice could be normalized by 2 Hz EA.

语种英语
WOS记录号WOS:000293456800001
项目编号2007CB512500 ; 30801491
资助机构National Basic Research Program ; National Natural Science Foundation of China
引用统计
被引频次:8[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
版本出版稿
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64860
专题北京大学基础医学院_神经生物学系
北京大学基础医学院
作者单位1.Peking Univ, Neurosci Res Inst, Beijing 100191, Peoples R China
2.Peking Univ, Sch Basic Med Sci, Dept Neurobiol, Beijing 100191, Peoples R China
3.Minist Educ, Key Lab Neurosci, Beijing 100191, Peoples R China
4.Minist Publ Hlth, Key Lab Neurosci, Beijing 100191, Peoples R China
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GB/T 7714
Li, Hong-Yu,Zhang, Rong,Cui, Cai-Lian,et al. Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2011(3):1-5.
APA Li, Hong-Yu,Zhang, Rong,Cui, Cai-Lian,Han, Ji-Sheng,&Wu, Liu-Zhen.(2011).Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE(3),1-5.
MLA Li, Hong-Yu,et al."Damage of Splenic T Lymphocyte Proliferation and Differentiation and Its Normalization by Electroacupuncture in Morphine-Dependent Mice Mode".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE .3(2011):1-5.
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