IR@PKUHSC  > 北京大学精神卫生研究所
学科主题精神卫生
The prevalence of family childhood adversities and their association with first onset of DSM-IV disorders in metropolitan China
Lee, S.1; Guo, W. J.2; Tsang, A.2; He, Y. L.3; Huang, Y. Q.4; Zhang, M. Y.3; Liu, Z. R.4; Shen, Y. C.4; Kessler, R. C.5
关键词Childhood adversity (CA) China family first onset mental disorders
刊名PSYCHOLOGICAL MEDICINE
2011
DOI10.1017/S0033291710000450
41期:1页:85-96
收录类别SCI ; SSCI
文章类型Article
WOS标题词Social Sciences ; Science & Technology
类目[WOS]Psychology, Clinical ; Psychiatry ; Psychology
资助者Pfizer Foundation ; WHO WMH Survey Initiative ; United States National Institute of Mental Health ; Mental Health Burden Study ; John D. and Catherine T. MacArthur Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization ; Eli Lilly and Company ; Ortho-McNeil Pharmaceutical, Inc. ; GlaxoSmithKline ; Bristol-Myers Squibb ; Sanofi-Aventis ; Johnson &amp ; Johnson Pharmaceuticals ; Ortho-McNeil Pharmaceuticals Inc. ; Pfizer Inc. ; Pfizer Foundation ; WHO WMH Survey Initiative ; United States National Institute of Mental Health ; Mental Health Burden Study ; John D. and Catherine T. MacArthur Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization ; Eli Lilly and Company ; Ortho-McNeil Pharmaceutical, Inc. ; GlaxoSmithKline ; Bristol-Myers Squibb ; Sanofi-Aventis ; Johnson &amp ; Johnson Pharmaceuticals ; Ortho-McNeil Pharmaceuticals Inc. ; Pfizer Inc.
研究领域[WOS]Psychology ; Psychiatry
关键词[WOS]NATIONAL-COMORBIDITY-SURVEY ; ADULT MENTAL-HEALTH ; SEXUAL-ABUSE ; PSYCHIATRIC-DISORDERS ; LIFE EVENTS ; HOUSEHOLD DYSFUNCTION ; 12-MONTH PREVALENCE ; MULTIPLE FORMS ; CHILDREN ; EXPERIENCES
英文摘要

Background. The prevalence of family childhood adversities (FCAs) and their joint effects on the first onset of subsequent mental disorders throughout the life course are rarely examined, especially in Asian communities.

Method. Face-to-face household interviews of 5201 people aged 18-70 years in Beijing and Shanghai were conducted by a multi-stage household probability sampling method. The first onsets of four broad groups of mental disorders and six categories of FCAs were assessed using The World Mental Health Composite International Diagnostic Interview (WMH-CIDI). Joint effects of FCAs were analyzed by the best fitting of several competitive multivariate models.

Results. FCAs were highly prevalent and inter-correlated. Half of them were in a family-dysfunction cluster. The best-fitting model included each of six types of FCA (with family-dysfunction FCAs being the strongest predictors), number of family-dysfunction FCAs, and number of other FCAs. Family-dysfunction FCAs had a significant subadditive association with subsequent disorders. Little specificity was found for the effects of particular FCAs with particular disorders. Predictive effects of FCAs reached the highest in ages 13-24 compared to ages 4-12 and >= 25. Estimates of population-attributable risk proportions indicated that all FCAs together explained 38.5% of all first-onset disorders.

Conclusions. Chinese children were exposed to a broad spectrum of inter-related FCAs, as found in Western countries. FCAs related to family dysfunction were especially associated with subsequent mental disorders. Biological and/or environmental factors that mediate these long-term effects should be studied in prospective research on broad groups of FCAs.

语种英语
所属项目编号R01MH070884 ; HHSN271200700030C ; R13-MH066849 ; R01-MH069864 ; R01 DA016558 ; FIRCA R01-TW006481
资助者Pfizer Foundation ; WHO WMH Survey Initiative ; United States National Institute of Mental Health ; Mental Health Burden Study ; John D. and Catherine T. MacArthur Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization ; Eli Lilly and Company ; Ortho-McNeil Pharmaceutical, Inc. ; GlaxoSmithKline ; Bristol-Myers Squibb ; Sanofi-Aventis ; Johnson &amp ; Johnson Pharmaceuticals ; Ortho-McNeil Pharmaceuticals Inc. ; Pfizer Inc. ; Pfizer Foundation ; WHO WMH Survey Initiative ; United States National Institute of Mental Health ; Mental Health Burden Study ; John D. and Catherine T. MacArthur Foundation ; US Public Health Service ; Fogarty International Center ; Pan American Health Organization ; Eli Lilly and Company ; Ortho-McNeil Pharmaceutical, Inc. ; GlaxoSmithKline ; Bristol-Myers Squibb ; Sanofi-Aventis ; Johnson &amp ; Johnson Pharmaceuticals ; Ortho-McNeil Pharmaceuticals Inc. ; Pfizer Inc.
WOS记录号WOS:000285478700010
Citation statistics
Cited Times:21[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/64906
Collection北京大学精神卫生研究所
作者单位1.Shanghai Mental Hlth Ctr, Shanghai, Peoples R China
2.Peking Univ, Inst Mental Hlth, Beijing, Peoples R China
3.Chinese Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
4.Chinese Univ Hong Kong, Hong Kong Mood Disorders Ctr, Hong Kong, Hong Kong, Peoples R China
5.Harvard Univ, Sch Med, Dept Hlth Care Policy, Cambridge, MA 02138 USA
Recommended Citation
GB/T 7714
Lee, S.,Guo, W. J.,Tsang, A.,et al. The prevalence of family childhood adversities and their association with first onset of DSM-IV disorders in metropolitan China[J]. PSYCHOLOGICAL MEDICINE,2011,41(1):85-96.
APA Lee, S..,Guo, W. J..,Tsang, A..,He, Y. L..,Huang, Y. Q..,...&Kessler, R. C..(2011).The prevalence of family childhood adversities and their association with first onset of DSM-IV disorders in metropolitan China.PSYCHOLOGICAL MEDICINE,41(1),85-96.
MLA Lee, S.,et al."The prevalence of family childhood adversities and their association with first onset of DSM-IV disorders in metropolitan China".PSYCHOLOGICAL MEDICINE 41.1(2011):85-96.
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