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学科主题: 临床医学
题名:
Handedness-related functional connectivity using low-frequency blood oxygenation level-dependent fluctuations
作者: He, Y; Zang, YF; Jiang, TZ; Gong, GL; Xie, S; Xiao, JX
关键词: blood oxygenation level-dependent ; cerebellum ; functional magnetic resonance imaging ; functional connectivity ; handedness ; low-frequency fluctuations ; resting state
刊名: NEUROREPORT
发表日期: 2006-01-23
卷: 17, 期:1, 页:5-8
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Neurosciences
研究领域[WOS]: Neurosciences & Neurology
关键词[WOS]: RESTING-STATE ; MOTOR CORTEX ; CEREBELLUM ; TASK ; MRI
英文摘要:

Functional neuroimaging studies of handedness have traditionally focused on exploring regionally activated discrepancies, yet little is known regarding the effect of handedness on functional connections of brain regions. Here, we reported the relationship between cerebellar functional connectivity patterns and handedness by lowfrequency blood oxygenation level-dependent fluctuations. Compared with the right-handers, the left-handers show higher cerebellar-prefrontal, cerebellar-parietal, and cerebellar-temporal functional connectivity, and lower cerebellar-limbic connectivity. Previous non-human primate studies have shown that these regions with known contributions to higher cognitive functions have afferent or efferent connections with the cerebellum. Our findings suggest that these observed low-frequency fluctuation correlations may reflect actually anatomic connections between the cerebellum and cerebral cortex, and the cerebellar involvement in higher function may be associated with handedness.

语种: 英语
WOS记录号: WOS:000234527700002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65003
Appears in Collections:北京大学第一临床医学院_放射治疗科_期刊论文

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作者单位: 1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
2.Peking Univ, Dept Radiol, Hosp 1, Beijing, Peoples R China

Recommended Citation:
He, Y,Zang, YF,Jiang, TZ,et al. Handedness-related functional connectivity using low-frequency blood oxygenation level-dependent fluctuations[J]. NEUROREPORT,2006,17(1):5-8.
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