IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Influence of acute normovolaemic haemodilution on bispectral index monitoring and propofol dose requirements
Dahaba, A. A.1; Rinnhofer, S.1; Wang, G.2; Xu, X.2; Liu, X. Y.2; Wu, X. M.2; Rehak, P. H.3; Metzler, H.1
关键词bispectral index normovolaemic haemodilution
刊名ACTA ANAESTHESIOLOGICA SCANDINAVICA
2008-07-01
DOI10.1111/j.1399-6576.2008.01629.x
52期:6页:815-820
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Anesthesiology
研究领域[WOS]Anesthesiology
关键词[WOS]SEVERE ISOVOLEMIC ANEMIA ; COGNITIVE FUNCTION ; ANESTHESIA ; HUMANS ; TRANSFUSION ; INDUCTION ; FREQUENCY ; INFUSION ; FENTANYL ; MEMORY
英文摘要

Background: Numerous medical and physiological conditions that might alter electroencephalography (EEG), such as hypoglycaemia, hypothermia or hypovolaemia, were shown to result in the bispectral Index (BIS) indicating an incorrect hypnotic state. Recently, acute normovolaemic haemodilution (ANH) was shown to be associated with significant impairment of cognitive functions that could alter EEG and consequently BIS monitoring, an EEG derived parameter.

Methods: In a randomised clinical study, we assessed the effect of ANH on BIS monitoring before induction and after propofol target controlled infusion (TCI) anaesthesia in 45 unmedicated patients randomly allocated to ANH with oxygen insufflation (oxygen group), ANH with air insufflation (air group), or control group.

Results: With ANH, mean BIS values briefly declined in the oxygen group (82 +/- 4) and air group (84 +/- 3) before returning to baseline values. The loss of consciousness time was significantly shorter, with fewer propofol TCI dose requirements, and BIS was significantly higher in the oxygen group (1.3 +/- 0.5 min, 2.41 +/- 0.15 mu g/ml, 73 +/- 7) and air group (1.2 +/- 0.6 min, 2.44 +/- 0.17 mu g/ml, 75 +/- 5), compared with the control group (1.7 +/- 0.4 min, 2.75 +/- 0.17 mu g/ml, 61 +/- 5), respectively. Whereas, there was no significant difference in BIS values between the oxygen group (38 +/- 7), air group (36 +/- 5) and control group (40 +/- 6) at propofol TCI 4 mu g/ml anaesthesia maintenance.

Conclusions: BIS values briefly declined with ANH before returning to baseline values before anaesthesia induction. Despite transient ANH enhancement of propofol effect during induction, there was no significant difference in BIS values with or without ANH during propofol maintenance of anaesthesia.

语种英语
WOS记录号WOS:000256683700014
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65023
专题北京大学第一临床医学院
作者单位1.Med Univ Graz, Dept Anaesthesiol & Intens Care Med, A-8036 Graz, Austria
2.Peking Univ, Hosp 1, Dept Anaesthesiol, Beijing 100871, Peoples R China
3.Med Univ Graz, Dept Surg, Biomed Engn & Comp Unit, A-8036 Graz, Austria
推荐引用方式
GB/T 7714
Dahaba, A. A.,Rinnhofer, S.,Wang, G.,et al. Influence of acute normovolaemic haemodilution on bispectral index monitoring and propofol dose requirements[J]. ACTA ANAESTHESIOLOGICA SCANDINAVICA,2008,52(6):815-820.
APA Dahaba, A. A..,Rinnhofer, S..,Wang, G..,Xu, X..,Liu, X. Y..,...&Metzler, H..(2008).Influence of acute normovolaemic haemodilution on bispectral index monitoring and propofol dose requirements.ACTA ANAESTHESIOLOGICA SCANDINAVICA,52(6),815-820.
MLA Dahaba, A. A.,et al."Influence of acute normovolaemic haemodilution on bispectral index monitoring and propofol dose requirements".ACTA ANAESTHESIOLOGICA SCANDINAVICA 52.6(2008):815-820.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Dahaba, A. A.]的文章
[Rinnhofer, S.]的文章
[Wang, G.]的文章
百度学术
百度学术中相似的文章
[Dahaba, A. A.]的文章
[Rinnhofer, S.]的文章
[Wang, G.]的文章
必应学术
必应学术中相似的文章
[Dahaba, A. A.]的文章
[Rinnhofer, S.]的文章
[Wang, G.]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。