IR@PKUHSC  > 北京大学第一临床医学院  > 泌尿外科
学科主题临床医学
Transurethral electrochemical treatment of benign prostatic hyperplasia
Zhang, M; Gong, K; Li, NC; Zeng, L; Na, YQ
关键词benign prostatic hyperplasia treatment electrochemistry
刊名CHINESE MEDICAL JOURNAL
2003
116期:1页:104-107
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Medicine, General & Internal
研究领域[WOS]General & Internal Medicine
关键词[WOS]CANCER ; ADRIAMYCIN
英文摘要

Objective To study the mechanism and feasibility of transurethral electrochemical therapy for the treatment,of benign prostatic hyperplasia (BPH).

Methods Between March 1998 and March 2000, specifically designed devices and catheters for electrochemical therapy were applied to 6 prostate specimens obtained by suprapubic prostatectomy in order to treat BPH, patients with urinary retention for whom surgery was contraindicated. Sixteen patients (with a mean age of 77.3 years old) underwent electrical treatment totaling 160 - 220 coulombs under topical urethral anesthesia for 68 - 132 min. The catheters remained inside the patient for 7 - 10 d.

Results Irreversible destructive changes occurred within cathodal tissue, while carbonization occurred within anodic tissue. The radius of tissue change was 7 - 8 mm and 1 - 2 mm, respectively. In vivo trial: 11 (69%) patients could be weaned off the catheters with satisfactory urination. Three months after therapy, the mean international prostate symptom score (IPSS) was 14.5, mean peak flow rate was 10.5 ml/s, and mean residual urine was 39 ml. No serious complications were observed.

Conclusion Transurethral electrochemical treatment is potentially a minimally invasive alternative for treatment if BPH, especially for elderly patients at high risk.

语种英语
WOS记录号WOS:000181239800023
引用统计
被引频次:3[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65061
专题北京大学第一临床医学院_泌尿外科
作者单位Peking Univ, Inst Urol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Zhang, M,Gong, K,Li, NC,et al. Transurethral electrochemical treatment of benign prostatic hyperplasia[J]. CHINESE MEDICAL JOURNAL,2003,116(1):104-107.
APA Zhang, M,Gong, K,Li, NC,Zeng, L,&Na, YQ.(2003).Transurethral electrochemical treatment of benign prostatic hyperplasia.CHINESE MEDICAL JOURNAL,116(1),104-107.
MLA Zhang, M,et al."Transurethral electrochemical treatment of benign prostatic hyperplasia".CHINESE MEDICAL JOURNAL 116.1(2003):104-107.
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