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学科主题: 临床医学
题名:
Transurethral electrochemical treatment of benign prostatic hyperplasia
作者: Zhang, M; Gong, K; Li, NC; Zeng, L; Na, YQ
关键词: benign prostatic hyperplasia ; treatment ; electrochemistry
刊名: CHINESE MEDICAL JOURNAL
发表日期: 2003
卷: 116, 期:1, 页:104-107
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Medicine, General & Internal
研究领域[WOS]: General & Internal Medicine
关键词[WOS]: CANCER ; ADRIAMYCIN
英文摘要:

Objective To study the mechanism and feasibility of transurethral electrochemical therapy for the treatment,of benign prostatic hyperplasia (BPH).

Methods Between March 1998 and March 2000, specifically designed devices and catheters for electrochemical therapy were applied to 6 prostate specimens obtained by suprapubic prostatectomy in order to treat BPH, patients with urinary retention for whom surgery was contraindicated. Sixteen patients (with a mean age of 77.3 years old) underwent electrical treatment totaling 160 - 220 coulombs under topical urethral anesthesia for 68 - 132 min. The catheters remained inside the patient for 7 - 10 d.

Results Irreversible destructive changes occurred within cathodal tissue, while carbonization occurred within anodic tissue. The radius of tissue change was 7 - 8 mm and 1 - 2 mm, respectively. In vivo trial: 11 (69%) patients could be weaned off the catheters with satisfactory urination. Three months after therapy, the mean international prostate symptom score (IPSS) was 14.5, mean peak flow rate was 10.5 ml/s, and mean residual urine was 39 ml. No serious complications were observed.

Conclusion Transurethral electrochemical treatment is potentially a minimally invasive alternative for treatment if BPH, especially for elderly patients at high risk.

语种: 英语
WOS记录号: WOS:000181239800023
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65061
Appears in Collections:北京大学第一临床医学院_泌尿外科_期刊论文

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作者单位: Peking Univ, Inst Urol, Beijing 100034, Peoples R China

Recommended Citation:
Zhang, M,Gong, K,Li, NC,et al. Transurethral electrochemical treatment of benign prostatic hyperplasia[J]. CHINESE MEDICAL JOURNAL,2003,116(1):104-107.
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