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学科主题: 口腔医学
题名:
Type II collagen and aggrecan mRNA expression by in situ hybridization in rabbit temporomandibular joint posterior attachment following disc displacement
作者: Gu, ZY; Feng, JY; Shibata, T; Hu, N; Zhang, ZK
关键词: temporomandibular joint ; disc displacement ; chondrocyte ; gene expression ; in situ hybridization
刊名: ARCHIVES OF ORAL BIOLOGY
发表日期: 2003
DOI: 10.1016/S0003-9969(02)00158-9
卷: 48, 期:1, 页:55-62
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dentistry, Oral Surgery & Medicine
研究领域[WOS]: Dentistry, Oral Surgery & Medicine
关键词[WOS]: SYNOVIAL CHONDROMATOSIS ; CRANIOMANDIBULAR JOINT ; INTERNAL DERANGEMENT ; CYTOKINES
英文摘要:

Pathological changes and mRNA expression were studied in the posterior attachment of 40 adult Japanese white rabbits. The right temporomandibular joints of 28 rabbits were subjected to surgical disc displacement. Joints were studied by histochemistry and in situ hybridization. The collagen in the posterior attachment became dense, especially near the posterior band of the disc. Chondrocytes; were found not only in the disc but also in the posterior attachment. Sometimes cartilage formation was seen. Type 11 collagen mRNA expression was first detected in the posterior attachment 4 days postoperatively and became progressively stronger with time. Aggrecan expression in the posterior attachment decreased at first, then increased gradually. It was concluded that, in the temporomandibular joint, chondrocytes appear in the posterior attachment as a result of biomechanical stimuli and the attachment becomes fibrocartilaginous following disc displacement. (C) 2002 Elsevier Science Ltd. All rights reserved.

语种: 英语
WOS记录号: WOS:000182686000007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65124
Appears in Collections:北京大学口腔医学院_期刊论文

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作者单位: 1.Zhejiang Univ, Hosp Stomatol, Dept Oral & Maxillofacial Surg, Hangzhou 310006, Zhejiang, Peoples R China
2.Yamagata Univ, Sch Med, Dept Dent & Oral Surg, Yamagata 99023, Japan
3.Zhejiang Univ, Hosp Stomatol, Dept Oral Pathol, Hangzhou 310006, Zhejiang, Peoples R China
4.Peking Univ, Dept Oral & Maxillofacial Surg, Sch Stomatol, Beijing 100871, Peoples R China

Recommended Citation:
Gu, ZY,Feng, JY,Shibata, T,et al. Type II collagen and aggrecan mRNA expression by in situ hybridization in rabbit temporomandibular joint posterior attachment following disc displacement[J]. ARCHIVES OF ORAL BIOLOGY,2003,48(1):55-62.
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