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学科主题临床医学
Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area
Sun, Z.; Wang, Y.; Ji, S.; Wang, K.; Zhao, Y.
关键词psoriasis body surface area image J
刊名SKIN RESEARCH AND TECHNOLOGY
2015-11-01
DOI10.1111/srt.12211
21期:4页:437-443
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dermatology
研究领域[WOS]Dermatology
关键词[WOS]INVOLVED SURFACE-AREA ; SEVERITY INDEX ; DISEASE ; QUANTIFICATION ; ERYTHEMA ; IMPACT
英文摘要

Background/aimsBody surface area is important in determining the severity of psoriasis. However, objective, reliable, and practical method is still in need for this purpose. We performed a computer image analysis (CIA) of psoriatic area using the image J freeware to determine whether this method could be used for objective evaluation of psoriatic area.

MethodsFifteen psoriasis patients were randomized to be treated with adalimumab or placebo in a clinical trial. At each visit, the psoriasis area of each body site was estimated by two physicians (E-method), and standard photographs were taken. The psoriasis area in the pictures was assessed with CIA using semi-automatic threshold selection (T-method), or manual selection (M-method, gold standard). The results assessed by the three methods were analyzed with reliability and affecting factors evaluated.

ResultsBoth T- and E-method correlated strongly with M-method, and T-method had a slightly stronger correlation with M-method. Both T- and E-methods had a good consistency between the evaluators. All the three methods were able to detect the change in the psoriatic area after treatment, while the E-method tends to overestimate.

ConclusionThe CIA with image J freeware is reliable and practicable in quantitatively assessing the lesional of psoriasis area.

语种英语
WOS记录号WOS:000362679600007
项目编号81201238
资助机构National Natural Science Foundation of China
引用统计
被引频次:5[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65138
专题北京大学第一临床医学院
作者单位Peking Univ, Hosp 1, Dept Dermatol & Venereol, Beijing 100034, Peoples R China
推荐引用方式
GB/T 7714
Sun, Z.,Wang, Y.,Ji, S.,et al. Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area[J]. SKIN RESEARCH AND TECHNOLOGY,2015,21(4):437-443.
APA Sun, Z.,Wang, Y.,Ji, S.,Wang, K.,&Zhao, Y..(2015).Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area.SKIN RESEARCH AND TECHNOLOGY,21(4),437-443.
MLA Sun, Z.,et al."Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area".SKIN RESEARCH AND TECHNOLOGY 21.4(2015):437-443.
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