IR@PKUHSC  > 北京大学第一临床医学院
学科主题临床医学
Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area
Sun, Z.; Wang, Y.; Ji, S.; Wang, K.; Zhao, Y.
关键词psoriasis body surface area image J
刊名SKIN RESEARCH AND TECHNOLOGY
2015-11-01
DOI10.1111/srt.12211
21期:4页:437-443
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Dermatology
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
研究领域[WOS]Dermatology
关键词[WOS]INVOLVED SURFACE-AREA ; SEVERITY INDEX ; DISEASE ; QUANTIFICATION ; ERYTHEMA ; IMPACT
英文摘要

Background/aimsBody surface area is important in determining the severity of psoriasis. However, objective, reliable, and practical method is still in need for this purpose. We performed a computer image analysis (CIA) of psoriatic area using the image J freeware to determine whether this method could be used for objective evaluation of psoriatic area.

MethodsFifteen psoriasis patients were randomized to be treated with adalimumab or placebo in a clinical trial. At each visit, the psoriasis area of each body site was estimated by two physicians (E-method), and standard photographs were taken. The psoriasis area in the pictures was assessed with CIA using semi-automatic threshold selection (T-method), or manual selection (M-method, gold standard). The results assessed by the three methods were analyzed with reliability and affecting factors evaluated.

ResultsBoth T- and E-method correlated strongly with M-method, and T-method had a slightly stronger correlation with M-method. Both T- and E-methods had a good consistency between the evaluators. All the three methods were able to detect the change in the psoriatic area after treatment, while the E-method tends to overestimate.

ConclusionThe CIA with image J freeware is reliable and practicable in quantitatively assessing the lesional of psoriasis area.

语种英语
所属项目编号81201238
资助者National Natural Science Foundation of China ; National Natural Science Foundation of China
WOS记录号WOS:000362679600007
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65138
Collection北京大学第一临床医学院
作者单位Peking Univ, Hosp 1, Dept Dermatol & Venereol, Beijing 100034, Peoples R China
Recommended Citation
GB/T 7714
Sun, Z.,Wang, Y.,Ji, S.,et al. Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area[J]. SKIN RESEARCH AND TECHNOLOGY,2015,21(4):437-443.
APA Sun, Z.,Wang, Y.,Ji, S.,Wang, K.,&Zhao, Y..(2015).Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area.SKIN RESEARCH AND TECHNOLOGY,21(4),437-443.
MLA Sun, Z.,et al."Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area".SKIN RESEARCH AND TECHNOLOGY 21.4(2015):437-443.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
谷歌学术
谷歌学术Similar articles in
[Sun, Z.]'s Articles
[Wang, Y.]'s Articles
[Ji, S.]'s Articles
百度学术
百度学术Similar articles in
[Sun, Z.]'s Articles
[Wang, Y.]'s Articles
[Ji, S.]'s Articles
必应学术
必应学术Similar articles in
[Sun, Z.]'s Articles
[Wang, Y.]'s Articles
[Ji, S.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.