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学科主题: 临床医学
题名:
Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area
作者: Sun, Z.; Wang, Y.; Ji, S.; Wang, K.; Zhao, Y.
关键词: psoriasis ; body surface area ; image J
刊名: SKIN RESEARCH AND TECHNOLOGY
发表日期: 2015-11-01
DOI: 10.1111/srt.12211
卷: 21, 期:4, 页:437-443
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Dermatology
研究领域[WOS]: Dermatology
关键词[WOS]: INVOLVED SURFACE-AREA ; SEVERITY INDEX ; DISEASE ; QUANTIFICATION ; ERYTHEMA ; IMPACT
英文摘要:

Background/aimsBody surface area is important in determining the severity of psoriasis. However, objective, reliable, and practical method is still in need for this purpose. We performed a computer image analysis (CIA) of psoriatic area using the image J freeware to determine whether this method could be used for objective evaluation of psoriatic area.

MethodsFifteen psoriasis patients were randomized to be treated with adalimumab or placebo in a clinical trial. At each visit, the psoriasis area of each body site was estimated by two physicians (E-method), and standard photographs were taken. The psoriasis area in the pictures was assessed with CIA using semi-automatic threshold selection (T-method), or manual selection (M-method, gold standard). The results assessed by the three methods were analyzed with reliability and affecting factors evaluated.

ResultsBoth T- and E-method correlated strongly with M-method, and T-method had a slightly stronger correlation with M-method. Both T- and E-methods had a good consistency between the evaluators. All the three methods were able to detect the change in the psoriatic area after treatment, while the E-method tends to overestimate.

ConclusionThe CIA with image J freeware is reliable and practicable in quantitatively assessing the lesional of psoriasis area.

语种: 英语
所属项目编号: 81201238
项目资助者: National Natural Science Foundation of China
WOS记录号: WOS:000362679600007
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65138
Appears in Collections:北京大学第一临床医学院_期刊论文

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作者单位: Peking Univ, Hosp 1, Dept Dermatol & Venereol, Beijing 100034, Peoples R China

Recommended Citation:
Sun, Z.,Wang, Y.,Ji, S.,et al. Computer-aided analysis with Image J for quantitatively assessing psoriatic lesion area[J]. SKIN RESEARCH AND TECHNOLOGY,2015,21(4):437-443.
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