IR@PKUHSC  > 北京大学第三临床医学院
学科主题临床医学
Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses
Dong, LM; Wang, C; Tian, JM; Zhang, LC; Song, WM
关键词bone morphogenetic protein hydroxyapatite osteoinduction
刊名RARE METAL MATERIALS AND ENGINEERING
2002-09-01
suppl.1页:505-508
收录类别SCI
文章类型Article
WOS标题词Science & Technology
类目[WOS]Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
研究领域[WOS]Materials Science ; Metallurgy & Metallurgical Engineering
英文摘要

For the purpose of developing a new implantable biomaterial that possesses good biocompatibility and osteogenetic capability, the bone morphogenetic protein and hydroxyapatite made into ossicle in advance were compounded to prepare ossicular replacement prostheses. The ossicular prostheses were implanted in the middle ears of rabbits. The specimens were observed by gross and light microscope to study the osteogenetic effect and to contrast with the pure HA specimens. The result showed that new bone was found at 6 weeks after the BMP/HA ossicular prostheses were implanted in the middle ears of rabbits. In the HA contrast, no new bone was seen. This indicates BMP/HA composite is better than pure HA and has good osteoinduction and biocompatibility.

语种中文
WOS记录号WOS:000179724300132
引用统计
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65252
专题北京大学第三临床医学院
作者单位1.Beijing Univ, Hosp 3, Beijing 100083, Peoples R China
2.Tsing Hua Univ, State Key Lab New Ceram & Fine Proc, Beijing 100084, Peoples R China
推荐引用方式
GB/T 7714
Dong, LM,Wang, C,Tian, JM,et al. Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses[J]. RARE METAL MATERIALS AND ENGINEERING,2002,suppl.1:505-508.
APA Dong, LM,Wang, C,Tian, JM,Zhang, LC,&Song, WM.(2002).Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses.RARE METAL MATERIALS AND ENGINEERING,suppl.1,505-508.
MLA Dong, LM,et al."Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses".RARE METAL MATERIALS AND ENGINEERING suppl.1(2002):505-508.
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