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学科主题: 临床医学
题名:
Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses
作者: Dong, LM; Wang, C; Tian, JM; Zhang, LC; Song, WM
关键词: bone morphogenetic protein ; hydroxyapatite ; osteoinduction
刊名: RARE METAL MATERIALS AND ENGINEERING
发表日期: 2002-09-01
卷: suppl.1, 页:505-508
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
研究领域[WOS]: Materials Science ; Metallurgy & Metallurgical Engineering
英文摘要:

For the purpose of developing a new implantable biomaterial that possesses good biocompatibility and osteogenetic capability, the bone morphogenetic protein and hydroxyapatite made into ossicle in advance were compounded to prepare ossicular replacement prostheses. The ossicular prostheses were implanted in the middle ears of rabbits. The specimens were observed by gross and light microscope to study the osteogenetic effect and to contrast with the pure HA specimens. The result showed that new bone was found at 6 weeks after the BMP/HA ossicular prostheses were implanted in the middle ears of rabbits. In the HA contrast, no new bone was seen. This indicates BMP/HA composite is better than pure HA and has good osteoinduction and biocompatibility.

语种: 中文
WOS记录号: WOS:000179724300132
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65252
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Beijing Univ, Hosp 3, Beijing 100083, Peoples R China
2.Tsing Hua Univ, State Key Lab New Ceram & Fine Proc, Beijing 100084, Peoples R China

Recommended Citation:
Dong, LM,Wang, C,Tian, JM,et al. Study on composite of bone morphogenetic protein and hydroxyapatite for ossicular replacement prostheses[J]. RARE METAL MATERIALS AND ENGINEERING,2002,suppl.1:505-508.
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