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学科主题: 临床医学
题名:
Intraocular Pressure Changes during Accommodation in Progressing Myopes, Stable Myopes and Emmetropes
作者: Liu, Yan; Lv, Huibin; Jiang, Xiaodan; Hu, Xiaodan; Zhang, Mingzhou; Li, Xuemin
刊名: PLOS ONE
发表日期: 2015-10-30
DOI: 10.1371/journal.pone.0141839
卷: 10, 期:10
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Multidisciplinary Sciences
研究领域[WOS]: Science & Technology - Other Topics
关键词[WOS]: GOLDMANN APPLANATION TONOMETER ; AXIAL LENGTH ; REBOUND TONOMETRY ; REFRACTIVE ERROR ; ICARE TONOMETER ; GLAUCOMA ; BIOMECHANICS ; BIOMETRICS ; THICKNESS ; SUBGROUP
英文摘要:

Purpose

To investigate the changes of intraocular pressure (IOP) induced by 3-diopter (3 D) accommodation in progressing myopes, stable myopes and emmetropes.

Design

Cross-sectional study.

Participants

318 subjects including 270 myopes and 48 emmetropes.

Methods

195 progressing myopes, 75 stable myopes and 48 emmetropes participated in this study. All subjects had their IOP measured using iCare rebound tonometer while accommodative stimuli of 0 D and 3 D were presented. Main Outcome Measures IOP values without accommodation and with 3 D accommodation were measured in all subjects. Baseline IOPs and IOP changes were compared within and between groups.

Results

There was no significant difference in IOPs between progressing myopes, stable myopes and emmetropes when no accommodation was induced (17.47 +/- 3.46, 16.62 +/- 2.98 and 16.80 +/- 3.62 respectively, p > 0.05). IOP experienced an insignificantly slight decrease after 3 D accommodation in three groups (mean change -0.19 +/- 2.16, -0.03 +/- 1.68 and -0.39 +/- 2.65 respectively, p > 0.05). Subgroup analysis showed in progressing myopic group, IOP of children (<18 years old) declined with accommodation while IOP of adults (>= 18 years) increased, and the difference was statistically significant (p = 0.008). However, after excluding the age factor, accommodation induced IOP changes of high progressing myopes (<=- 6 D), low, moderate and non- myopes (>-6 D) was not significantly different after Bonferroni correction (p = 0.838).

Conclusions

Although no difference was detected between the baseline IOPs and accommodation induced IOP changes in progressing myopes, stable myopes and emmetropes, this study found accommodation could cause transient IOP elevation in adult progressing myopes.

语种: 英语
WOS记录号: WOS:000363920800084
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65269
Appears in Collections:北京大学第三临床医学院_眼科_期刊论文

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作者单位: Peking Univ, Hosp 3, Dept Ophthalmol, Beijing 100871, Peoples R China

Recommended Citation:
Liu, Yan,Lv, Huibin,Jiang, Xiaodan,et al. Intraocular Pressure Changes during Accommodation in Progressing Myopes, Stable Myopes and Emmetropes[J]. PLOS ONE,2015,10(10).
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