|A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing|
|关键词||allergy CAPB cocamidopropyl betaine contact dermatitis cosmetics dimethylaminopropylamine DMAPA patch test prevalence surfactant|
|WOS标题词||Science & Technology|
|类目[WOS]||Allergy ; Dermatology|
|研究领域[WOS]||Allergy ; Dermatology|
Background: The prevalence of sensitization to cocamidopropyl betaine (CAPB) in China has not been reported.
Objective: This study is to evaluate the prevalence of CAPB sensitization in patients patch tested in Peking University Third Hospital, Beijing.
Methods: 429 consecutive patients with suspected allergic contact dermatitis were patch tested with CAPB 1.0% aqueous, 3-dimethylaminopropylamine (DMAPA) 1.0% aqueous as well as a modified European standard series of allergens from June 2005 to August 2006.
Results: 42 patients (9.8%) had a positive reaction to CAPB. 25 of them (59.5%) were considered relevant. Of those, 7 were head and/or neck dermatitis, 4 hand dermatitis, 1 cheilitis, and the other 13 patients were widespread dermatitis. 10 out of 429 (2.3%) patients reacted to DMAPA. Of those, 8 were relevant and 6 of them also reacted to CAPB.
Conclusion: The rate of CAPB sensitization in our study is higher than previously reported elsewhere. CAPB is a common cosmetic allergen in Beijing. Both CAPB and DMAPA should be tested in patients with suspected cosmetic dermatitis.
|作者单位||Peking Univ, Hosp 3, Dept Dermatol, Beijing 100083, Peoples R China|
|Li, Lin-Feng. A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing[J]. CONTACT DERMATITIS,2008,58(1):24-27.|
|APA||Li, Lin-Feng.(2008).A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing.CONTACT DERMATITIS,58(1),24-27.|
|MLA||Li, Lin-Feng."A study of the sensitization rate to cocamidopropyl betaine in patients patch tested in a university hospital of Beijing".CONTACT DERMATITIS 58.1(2008):24-27.|