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学科主题: 药学
题名:
Chemical Analysis of the Chinese Herbal Medicine Turmeric (Curcuma longa L.)
作者: Li, Rui; Xiang, Cheng; Zhang, Xing; Guo, De-An; Ye, Min
关键词: Curcuma longa L ; Sesquiterpenes ; Curcuminoids ; Chemical analysis ; Quality control ; Chinese herbal medicine
刊名: CURRENT PHARMACEUTICAL ANALYSIS
发表日期: 2010-11-01
卷: 6, 期:4, 页:256-268
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Pharmacology & Pharmacy
研究领域[WOS]: Pharmacology & Pharmacy
关键词[WOS]: CHEMOPREVENTIVE AGENT CURCUMIN ; PRESSURIZED-LIQUID-EXTRACTION ; CHROMATOGRAPHY-MASS-SPECTROMETRY ; KAPPA-B ACTIVATION ; I CLINICAL-TRIAL ; HPLC METHOD ; QUANTITATIVE-DETERMINATION ; ALZHEIMERS-DISEASE ; RAT PLASMA ; BISABOLANE SESQUITERPENOIDS
英文摘要:

Turmeric (Curcuma longa L., Zingiberaceae family) is a well known Chinese herbal medicine. It possesses diverse pharmacologic effects including antioxidant, anti-inflammatory, antiproliferative and antiangiogenic activities. The main bioactive constituents of C. longa include sesquiterpenes, which are responsible for its aroma, and curcuminoids, which contribute to its bright yellow color. Both sesquiterpenes and curcuminoids exhibit great potential as therapeutic agents for various diseases including colon cancer, pancreatic cancer, diabetes and Alzheimer′s disease. Particularly, curcumin, one of the major curcuminoids of turmeric, has been proved to be effective in cancer treatment and prevention by recent phase I clinical trials. In order to ensure the efficacy and safety of turmeric in clinical applications, sensitive and accurate analytical methods are of significance for the comprehensive quality control of C. longa. This review summarizes recent progress in the chemical analysis of sesquiterpenes and curcuminoids in turmeric.

语种: 英语
所属项目编号: 985-2-119-121
项目资助者: Peking University Health Science Center
WOS记录号: WOS:000284942100004
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65388
Appears in Collections:北京大学药学院_期刊论文

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作者单位: Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China

Recommended Citation:
Li, Rui,Xiang, Cheng,Zhang, Xing,et al. Chemical Analysis of the Chinese Herbal Medicine Turmeric (Curcuma longa L.)[J]. CURRENT PHARMACEUTICAL ANALYSIS,2010,6(4):256-268.
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