北京大学医学部机构知识库
Advanced  
IR@PKUHSC  > 北京大学临床肿瘤学院  > 病理科  > 期刊论文
学科主题: 临床医学
题名:
Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer
作者: Kakudo, Kennichi1,2; Bai, Yanhua3; Liu, Zhiyan4; Ozaki, Takashi2
关键词: borderline malignancy ; diagnosis ; follicular variant papillary carcinoma ; treatment ; thyroid gland
刊名: PATHOLOGY INTERNATIONAL
发表日期: 2012-03-01
DOI: 10.1111/j.1440-1827.2011.02773.x
卷: 62, 期:3, 页:155-160
收录类别: SCI
文章类型: Review
WOS标题词: Science & Technology
类目[WOS]: Pathology
研究领域[WOS]: Pathology
关键词[WOS]: PROGNOSTIC-FACTORS ; DIFFERENTIAL-DIAGNOSIS ; GENETIC ALTERATIONS ; OBSERVER VARIATION ; FOLLOW-UP ; TUMORS ; GALECTIN-3 ; GLAND ; EXPRESSION ; FEATURES
英文摘要:

Papillary thyroid carcinoma (PTC) has long been diagnosed based on its unique nuclear features (PTC-N); however, significant observer discrepancies have been reported in the diagnosis of encapsulated follicular patterned lesions (EnFPLs), because the threshold of PTC-N is subjective. An equivocal PTC-N may often occur in non-invasive EnFPLs and benign/malignant disagreements often create serious problems for patients′ treatment. This review collects recent publications focusing on the so-called encapsulated follicular variant of papillary thyroid carcinoma (EnFVPTC) and tries to emphasize problems in the histopathological diagnosis of this spectrum of tumors, which covers encapsulated common-type PTC (EncPTC), EnFVPTC, well-differentiated tumor of uncertain malignant potential (WDT-UMP), follicular adenoma (FA) with equivocal PTC-N and minimally invasive follicular carcinoma (mFTC). We propose that EnFVPTC and other EnFPLs with equivocal PTC-N should be classified into a unified category of borderline malignancy, such as well-differentiated tumor of uncertain behavior (WDT-UB), based on their homogeneous excellent outcome. It is suggested that the unified nomenclature of these lesions may be helpful to reduce significant observer disagreements in diagnosis, because complete agreement in the diagnosis of an EncPTC, EnFVPTC or FA by all pathologists may be not possible for this problematic group of tumors. In conclusion, a malignant diagnosis of EnFVPTC should not be used to cover this spectrum of tumors until uncertainty about the nature of this lesion is settled, whether it is benign, precancerous or malignant.

语种: 英语
WOS记录号: WOS:000300709800001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65417
Appears in Collections:北京大学临床肿瘤学院_病理科_期刊论文

Files in This Item:

There are no files associated with this item.


作者单位: 1.Wakayama Med Univ, Dept Human Pathol, Wakayama, Japan
2.Kobe Tokiwa Univ, Fac Hlth Sci, Dept Med Technol, Nagata Ku, Kobe, Hyogo 6530838, Japan
3.Peking Univ, Dept Pathol, Beijing Canc Hosp & Inst,Sch Oncol, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100871, Peoples R China
4.Shandong Univ, Sch Med, Dept Pathol & Pathophysiol, Jinan 250100, Peoples R China

Recommended Citation:
Kakudo, Kennichi,Bai, Yanhua,Liu, Zhiyan,et al. Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer[J]. PATHOLOGY INTERNATIONAL,2012,62(3):155-160.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Kakudo, Kennichi]'s Articles
[Bai, Yanhua]'s Articles
[Liu, Zhiyan]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Kakudo, Kennichi]‘s Articles
[Bai, Yanhua]‘s Articles
[Liu, Zhiyan]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!
Copyright © 2007-2017  北京大学医学部 - Feedback
Powered by CSpace