IR@PKUHSC  > 北京大学临床肿瘤学院  > 病理科
学科主题临床医学
Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer
Kakudo, Kennichi1,2; Bai, Yanhua3; Liu, Zhiyan4; Ozaki, Takashi2
关键词borderline malignancy diagnosis follicular variant papillary carcinoma treatment thyroid gland
刊名PATHOLOGY INTERNATIONAL
2012-03-01
DOI10.1111/j.1440-1827.2011.02773.x
62期:3页:155-160
收录类别SCI
文章类型Review
WOS标题词Science & Technology
类目[WOS]Pathology
研究领域[WOS]Pathology
关键词[WOS]PROGNOSTIC-FACTORS ; DIFFERENTIAL-DIAGNOSIS ; GENETIC ALTERATIONS ; OBSERVER VARIATION ; FOLLOW-UP ; TUMORS ; GALECTIN-3 ; GLAND ; EXPRESSION ; FEATURES
英文摘要

Papillary thyroid carcinoma (PTC) has long been diagnosed based on its unique nuclear features (PTC-N); however, significant observer discrepancies have been reported in the diagnosis of encapsulated follicular patterned lesions (EnFPLs), because the threshold of PTC-N is subjective. An equivocal PTC-N may often occur in non-invasive EnFPLs and benign/malignant disagreements often create serious problems for patients′ treatment. This review collects recent publications focusing on the so-called encapsulated follicular variant of papillary thyroid carcinoma (EnFVPTC) and tries to emphasize problems in the histopathological diagnosis of this spectrum of tumors, which covers encapsulated common-type PTC (EncPTC), EnFVPTC, well-differentiated tumor of uncertain malignant potential (WDT-UMP), follicular adenoma (FA) with equivocal PTC-N and minimally invasive follicular carcinoma (mFTC). We propose that EnFVPTC and other EnFPLs with equivocal PTC-N should be classified into a unified category of borderline malignancy, such as well-differentiated tumor of uncertain behavior (WDT-UB), based on their homogeneous excellent outcome. It is suggested that the unified nomenclature of these lesions may be helpful to reduce significant observer disagreements in diagnosis, because complete agreement in the diagnosis of an EncPTC, EnFVPTC or FA by all pathologists may be not possible for this problematic group of tumors. In conclusion, a malignant diagnosis of EnFVPTC should not be used to cover this spectrum of tumors until uncertainty about the nature of this lesion is settled, whether it is benign, precancerous or malignant.

语种英语
WOS记录号WOS:000300709800001
引用统计
被引频次:29[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.bjmu.edu.cn/handle/400002259/65417
专题北京大学临床肿瘤学院_病理科
作者单位1.Wakayama Med Univ, Dept Human Pathol, Wakayama, Japan
2.Kobe Tokiwa Univ, Fac Hlth Sci, Dept Med Technol, Nagata Ku, Kobe, Hyogo 6530838, Japan
3.Peking Univ, Dept Pathol, Beijing Canc Hosp & Inst,Sch Oncol, Key Lab Carcinogenesis & Translat Res,Minist Educ, Beijing 100871, Peoples R China
4.Shandong Univ, Sch Med, Dept Pathol & Pathophysiol, Jinan 250100, Peoples R China
推荐引用方式
GB/T 7714
Kakudo, Kennichi,Bai, Yanhua,Liu, Zhiyan,et al. Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer[J]. PATHOLOGY INTERNATIONAL,2012,62(3):155-160.
APA Kakudo, Kennichi,Bai, Yanhua,Liu, Zhiyan,&Ozaki, Takashi.(2012).Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer.PATHOLOGY INTERNATIONAL,62(3),155-160.
MLA Kakudo, Kennichi,et al."Encapsulated papillary thyroid carcinoma, follicular variant: A misnomer".PATHOLOGY INTERNATIONAL 62.3(2012):155-160.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Kakudo, Kennichi]的文章
[Bai, Yanhua]的文章
[Liu, Zhiyan]的文章
百度学术
百度学术中相似的文章
[Kakudo, Kennichi]的文章
[Bai, Yanhua]的文章
[Liu, Zhiyan]的文章
必应学术
必应学术中相似的文章
[Kakudo, Kennichi]的文章
[Bai, Yanhua]的文章
[Liu, Zhiyan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。