|Practice of sedation and the perception of discomfort during mechanical ventilation in Chinese intensive care units|
|Ma, Penglin1; Liu, Jingtao1; Xi, Xiuming2; Du, Bin3; Yuan, Xu4; Lin, Hongyuan5; Wang, Yu1; Su, Jinwen1; Zeng, Lin6|
|关键词||Sedation Discomfort Ventilation|
|刊名||JOURNAL OF CRITICAL CARE|
|WOS标题词||Science & Technology|
|类目[WOS]||Critical Care Medicine|
|研究领域[WOS]||General & Internal Medicine|
|关键词[WOS]||CRITICALLY-ILL PATIENTS ; CLINICAL-PRACTICE GUIDELINES ; PATIENTS RECOLLECTIONS ; ANALGESIA ; ADULT ; INTERRUPTION ; EXPERIENCES ; MEMORIES|
Purpose: The purpose of this study was to investigate sedation practices and the perception of discomfort during mechanical ventilation in Chinese intensive care units (ICUs).
Material and Method: A prospective, observational, cohort study was conducted in 31 Chinese ICUs in academic hospitals from June 15 to August 15, 2006. Conscious patients who were discharged from the ICU after mechanical ventilation were consecutively included. Using a standardized questionnaire, a personal interview was conducted with each patient within 2 days after discharge from the ICU. Patients were asked about recollections of emotional and physical discomfort. Sedation and analgesia administration data were collected from patient records.
Results: As prospectively defined, 83 (50.9%) of 163 patients met criteria for complex-mixed discomfort (ie, at least I emotional and 2 physical disturbances). Similarly, 79.1% of patients remembered seriously uncomfortable experiences associated with 1 of the 3 predefined sources. Both protocolized sedation and continuous sedation without a defined protocol, but not intermittent sedation, significantly reduced the relative risk of complex-mixed discomfort occurrences (P < .001). Notably, only 14.7% of patients received protocolized sedation, and 61 (37.4%) of 163 were not given any sedatives.
Conclusion: Mechanically ventilated ICU patients in Chinese academic hospitals were inadequately treated for discomfort. Protocolized sedation can effectively improve patient comfort. (C) 2010 Elsevier Inc. All rights reserved.
|作者单位||1.Chinese Peoples Liberat Army Gen Hosp, Affiliated Hosp 2, Dept Crit Care Med, Beijing 100091, Peoples R China|
2.Capital Med Univ, Fu Xing Hosp, SICU, Beijing 100038, Peoples R China
3.Beijing Union Med Coll Hosp, Med ICU, Beijing 100730, Peoples R China
4.Capital Med Univ, Tong Rong Hosp, SICU, Beijing 100730, Peoples R China
5.Chinese Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Crit Care Med, Beijing 100048, Peoples R China
6.Peking Univ, Hosp 3, Res Ctr Clin Epidemiol, Beijing 100191, Peoples R China
|Ma, Penglin,Liu, Jingtao,Xi, Xiuming,et al. Practice of sedation and the perception of discomfort during mechanical ventilation in Chinese intensive care units[J]. JOURNAL OF CRITICAL CARE,2010,25(3):451-457.|
|APA||Ma, Penglin.,Liu, Jingtao.,Xi, Xiuming.,Du, Bin.,Yuan, Xu.,...&Zeng, Lin.(2010).Practice of sedation and the perception of discomfort during mechanical ventilation in Chinese intensive care units.JOURNAL OF CRITICAL CARE,25(3),451-457.|
|MLA||Ma, Penglin,et al."Practice of sedation and the perception of discomfort during mechanical ventilation in Chinese intensive care units".JOURNAL OF CRITICAL CARE 25.3(2010):451-457.|