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学科主题: 临床医学
题名:
COPD in Chinese nonsmokers
作者: Zhou, Y.1; Wang, C.2,8; Yao, W.3; Chen, P.4; Kang, J.5; Huang, S.6; Chen, B.7; Wang, C.; Ni, D.9; Wang, X.10; Wang, D.11; Liu, S.1,12; Lu, J.13; Zheng, J.1; Zhong, N.1; Ran, P.1
关键词: Biomass smoke ; chronic obstructive pulmonary disease ; environmental tobacco smoke ; epidemiology ; nonsmokers
刊名: EUROPEAN RESPIRATORY JOURNAL
发表日期: 2009-03-01
DOI: 10.1183/09031936.00084408
卷: 33, 期:3, 页:509-518
收录类别: SCI
文章类型: Article
WOS标题词: Science & Technology
类目[WOS]: Respiratory System
研究领域[WOS]: Respiratory System
关键词[WOS]: OBSTRUCTIVE PULMONARY-DISEASE ; INDOOR AIR-POLLUTION ; RESPIRATORY-DISEASES ; BIOMASS FUELS ; RISK-FACTORS ; PREVALENCE ; POPULATION ; CHILDHOOD ; EXPOSURE ; ADULTS
英文摘要:

Little is known about chronic obstructive pulmonary disease (COPD) in Chinese nonsmokers. The present study aimed to investigate the profiles of COPD among nonsmokers based on the Chinese Epidemiological Survey of COPD (CESCOPD).

In the CESCOPD, 20,245 subjects aged 40 yrs or older were interviewed with questionnaires and spirometry tests. Subjects with a post-bronchodilator forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio of <0.70 were identified as having COPD. Data of 12,471 nonsmokers and 1,024 smoking COPD patients were analysed in the current study.

The overall prevalence of COPD among nonsmokers was 5.2% (95% confidence interval 4.8-5.6). Being male, of advanced age, lower body mass index (BMI) and lower educational level, having exposure to environmental tobacco smoke, coal and/or biomass smoke, poor ventilation in the kitchen, a family history of respiratory disease and recurrent childhood cough were all independently associated with a higher risk of having COPD among nonsmokers. Nonsmokers with respiratory symptoms without airflow limitation showed a somewhat different pattern of risk factors. Nonsmokers with COPD were less likely to present with chronic productive coughs and lower BMI, while more likely to have received a physician diagnosis of asthma and respiratory diseases in childhood, than smokers with COPD.

Chronic obstructive pulmonary disease is prevalent among Chinese nonsmokers, and nonsmoking chronic obstructive pulmonary disease may have different profiles from smoking chronic obstructive pulmonary disease.

语种: 英语
所属项目编号: 2001BA703B03 ; B30301
项目资助者: Chinese Central Government ; Guangdong Key Research Project (China)
WOS记录号: WOS:000263942400011
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.bjmu.edu.cn/handle/400002259/65444
Appears in Collections:北京大学第三临床医学院_期刊论文

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作者单位: 1.Guangzhou Med Univ, Affiliated Hosp 1, Guangzhou Inst Resp Dis, State Key Lab Resp Dis, Guangzhou 510182, Guangdong, Peoples R China
2.Capital Univ Med Sci, Beijing Chaoyang Hosp, Beijing Inst Resp Med, Beijing, Peoples R China
3.Peking Univ, Hosp 3, Beijing 100871, Peoples R China
4.Shenyang Mil Gen Hosp, Shenyang, Peoples R China
5.China Med Univ, Affiliated Hosp 1, Shenyang, Peoples R China
6.Shanghai Jiao Tong Univ, Ruijin Hosp, Shanghai 200030, Peoples R China
7.Tianjin Med Univ, Gen Hosp, Tianjin, Peoples R China
8.Third Med Univ, Xinqiao Hosp, Chongqing, Peoples R China
9.Fourth Mil Med Univ, Xijing Hosp, Xian 710032, Peoples R China
10.First Municipal People Hosp Shaoguan, Shaoguan, Peoples R China
11.Second Hosp Liwan Dist Guangzhou, Guangzhou, Guangdong, Peoples R China
12.Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China
13.Guangzhou Med Univ, Dept Epidermiol, Guangzhou, Guangdong, Peoples R China

Recommended Citation:
Zhou, Y.,Wang, C.,Yao, W.,et al. COPD in Chinese nonsmokers[J]. EUROPEAN RESPIRATORY JOURNAL,2009,33(3):509-518.
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